Nanostructured devices based on block copolymer assemblies for drug delivery: designing structures for enhanced drug function

N Nishiyama, K Kataoka - Polymer Therapeutics II, 2006 - Springer
Block copolymers spontaneously assemble into nanoscaled polymeric micelles, which have
significant potential as drug carriers. Following much work in related fields over the last …

Fabrication of micellar nanoparticles for drug delivery through the self-assembly of block copolymers

ZL Tyrrell, Y Shen, M Radosz - Progress in Polymer Science, 2010 - Elsevier
Micelles formed through the self-assembly of block copolymers have been widely used to
encapsulate highly hydrophobic drugs to increase their effective solubility. However, this …

Mixed micelles self-assembled from block copolymers for drug delivery

ABE Attia, ZY Ong, JL Hedrick, PP Lee, PLR Ee… - Current Opinion in …, 2011 - Elsevier
Mixed micelles self-assembled from two or more dissimilar block copolymers provide a
direct and convenient approach to improve physical stability and enhance drug loading …

Polymeric micelles as new drug carriers

GS Kwon, T Okano - Advanced drug delivery reviews, 1996 - Elsevier
Advances in block copolymer syntheses have led to polymeric micelles that may serve as
nanoscopic drug carriers. For drug delivery, micelles were prepared from biocompatible and …

Block copolymer micelles for drug delivery: design, characterization and biological significance

K Kataoka, A Harada, Y Nagasaki - Advanced drug delivery reviews, 2012 - Elsevier
Recently, colloidal carrier systems have been receiving much attention in the field of drug
targeting because of their high loading capacity for drugs as well as their unique disposition …

Block copolymer micelles in nanomedicine applications

H Cabral, K Miyata, K Osada, K Kataoka - Chemical reviews, 2018 - ACS Publications
Polymeric micelles are demonstrating high potential as nanomedicines capable of
controlling the distribution and function of loaded bioactive agents in the body, effectively …

Block copolymer micelles: preparation, characterization and application in drug delivery

G Gaucher, MH Dufresne, VP Sant, N Kang… - Journal of controlled …, 2005 - Elsevier
Block copolymer micelles are generally formed by the self-assembly of either amphiphilic or
oppositely charged copolymers in aqueous medium. The hydrophilic and hydrophobic …

Polymeric micelles for nano-scale drug delivery

K Miyata, RJ Christie, K Kataoka - Reactive and Functional Polymers, 2011 - Elsevier
This review describes the design of polymeric micelles from block copolymers and their
performances as nano-scale drug delivery systems, with emphasis on our recent work. The …

Advanced drug delivery devices via self-assembly of amphiphilic block copolymers

A Rösler, GWM Vandermeulen, HA Klok - Advanced drug delivery reviews, 2012 - Elsevier
Amphiphilic block copolymers are well established as building blocks for the preparation of
micellar drug carriers. Over the past decade, the effectiveness of such self-assembled drug …

Current state, achievements, and future prospects of polymeric micelles as nanocarriers for drug and gene delivery

N Nishiyama, K Kataoka - Pharmacology & therapeutics, 2006 - Elsevier
Polymeric micelles, self-assemblies of block copolymers, are promising nanocarrier systems
for drug and gene delivery. Until now, several micellar formulations of antitumor drugs have …