Capillary leukocytes, microaggregates, and the response to hypoxemia in the microcirculation of coronavirus disease 2019 patients

E Favaron, C Ince, MP Hilty, B Ergin… - Critical Care …, 2021 - journals.lww.com
OBJECTIVES: In this study, we hypothesized that coronavirus disease 2019 patients exhibit
sublingual microcirculatory alterations caused by inflammation, coagulopathy, and …

Microcirculation alterations in severe COVID-19 pneumonia

VSK Edul, JFC Eguillor, G Ferrara, E Estenssoro… - Journal of critical …, 2021 - Elsevier
Purpose To assess the presence of sublingual microcirculatory and skin perfusion
alterations in COVID-19 pneumonia. Materials and methods This is a preliminary report of a …

Microcirculatory alterations in critically Ill patients with COVID-19-associated acute respiratory distress syndrome

U Di Dedda, A Ascari, A Fantinato, D Fina… - Journal of Clinical …, 2022 - mdpi.com
Background: Presently, a number of specific observations have been performed on
microcirculatory function in a coronavirus disease-19 (COVID-19) setting. We hypothesized …

Microvascular flow alterations in critically ill COVID-19 patients: A prospective study

O Abou-Arab, C Beyls, A Khalipha, M Guilbart… - PLoS …, 2021 - journals.plos.org
Background Data on microcirculatory pattern of COVID-19 critically ill patients are scarce.
The objective was to compare sublingual microcirculation parameters of critically ill patients …

Microcirculatory, endothelial, and inflammatory responses in critically ill patients with COVID-19 are distinct from those seen in septic shock: a case control study

SD Hutchings, J Watchorn, F Trovato, S Napoli… - Shock, 2021 - journals.lww.com
Critically ill patients with COVID-19 infection frequently exhibit a hyperinflammatory
response and develop organ failures; however, the underlying mechanisms are unclear. We …

Predictors of Mortality in Critically Ill COVID‐19 Patients Demanding High Oxygen Flow: A Thin Line between Inflammation, Cytokine Storm, and Coagulopathy

V Popadic, S Klasnja, N Milic, N Rajovic… - Oxidative Medicine …, 2021 - Wiley Online Library
Introduction. Mortality among critically ill COVID‐19 patients remains relatively high despite
different potential therapeutic modalities being introduced recently. The treatment of critically …

Pericyte alteration sheds light on micro-vasculopathy in COVID-19 infection

N Cardot-Leccia, T Hubiche, J Dellamonica… - Intensive care …, 2020 - Springer
Dear Editor, Understanding the mechanisms involved in SARS-CoV-2 infection is crucial to
provide more efficient therapeutic approaches. Here, we report the histological patterns of …

[HTML][HTML] The association of inflammatory cytokines in the pulmonary pathophysiology of respiratory failure in critically ill patients with coronavirus disease 2019

S Stukas, RL Hoiland, J Cooper, S Thiara… - Critical care …, 2020 - journals.lww.com
Objectives: The majority of coronavirus disease 2019 mortality and morbidity is attributable
to respiratory failure from severe acute respiratory syndrome coronavirus 2 infection. The …

A high neutrophil-lymphocyte ratio is associated with increased morbidity and mortality in patients with coronavirus disease 2019

AH King, O Mehkri, P Rajendram, X Wang… - Critical Care …, 2021 - journals.lww.com
Objectives: The neutrophil-lymphocyte ratio is an inexpensive and simple inflammatory
marker. A higher ratio, indicative of an acute hyperinflammatory response or diminished …

Endothelial injury and glycocalyx degradation in critically ill coronavirus disease 2019 patients: implications for microvascular platelet aggregation

DD Fraser, EK Patterson, M Slessarev… - Critical Care …, 2020 - journals.lww.com
Objectives: Coronavirus disease 2019 is caused by the novel severe acute respiratory
syndrome coronavirus 2 virus. Patients admitted to the ICU suffer from microvascular …