Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside
reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), gained a definitive …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) have, in addition to the nucleoside
reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs), gained a definitive …

It is almost 20 years since NNRTIs were identified as a new class of antiretroviral drugs for
the treatment of HIV-1 infection. Although they belong to different and diverse chemical …

Background: After the initial discovery of 1-(2-hydroxyethoxymethyl)-6-(phenylthio) thymine
(HEPT) and tetrahydroimidazo [4, 5, 1-jk][1, 4] benzodiazepin-2 (1H)-one and thione (TIBO) …

The first compounds ever shown to specifically inhibit HIV-1 (human immunodeficiency virus
type l), but not HIV-2 (human immunodeficiency virus type 2), replication were the 1-(2 …

Almost fifteen years ago, the first non-nucleoside reverse transcriptase (RT) inhibitor
(NNRTI) lead compounds have been discovered. Nowadays, three NNRTIs are approved for …

Human immunodeficiency virus (HIV) infection is now pandemic. Targeting HIV-1 reverse
transcriptase (HIV-1 RT) has been considered as one of the most successful targets for the …

Non‐nucleoside reverse transcriptase (RT) inhibitors (NNRTIs) have become an inherent
ingredient of the drug combination schemes that are currently used in the treatment of …

Along with nucleoside reverse transcriptase inhibitors (NRTIs) and protease inhibitors (PIs),
nonnucleoside reverse transcriptase inhibitors (NNRTIs) have gained a definitive and …

Non-nucleoside reverse transcriptase inhibitors (NNRTIs) are promising drugs for the
treatment of HIV when used in combination with other anti-HIV drugs such as nucleoside …