SARS-CoV-2 and COVID-19: from the bench to the bedside

S Romagnoli, A Peris, AR De Gaudio… - Physiological …, 2020 - journals.physiology.org
First isolated in China in early 2020, Severe Acute Respiratory Syndrome Coronavirus-2
(SARS-CoV-2) is the novel coronavirus responsible for the ongoing pandemic of …

[HTML][HTML] A glimpse into the eye of the COVID-19 cytokine storm

K Kuppalli, AL Rasmussen - EBioMedicine, 2020 - thelancet.com
The pathogenesis of pandemic coronavirus disease-2019 (COVID-19) caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2) likely depends heavily on …

The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

Risk factors for adverse outcomes of COVID-19 patients: Possible basis for diverse responses to the novel coronavirus SARS-CoV-2

M Ghaebi, S Tahmasebi, M Jozghorbani, A Sadeghi… - Life sciences, 2021 - Elsevier
Abstract Severe coronavirus disease 2019 (COVID-19) caused by the Severe Acute
Respiratory Syndrome coronavirus 2 (SARS-CoV-2) is characterized by an unpredictable …

[HTML][HTML] A review on function and side effects of systemic corticosteroids used in high-grade COVID-19 to prevent cytokine storms

MA Langarizadeh, MR Tavakoli, A Abiri… - EXCLI …, 2021 - ncbi.nlm.nih.gov
In December 2019, a cluster of pneumonia caused by a novel coronavirus (2019-nCoV),
officially known as severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …

COVID-19: inflammatory profile

Y Wang, S Perlman - Annual review of medicine, 2022 - annualreviews.org
Infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of
coronavirus disease 2019 (COVID-19), has resulted in a pandemic that has had widespread …

[HTML][HTML] A deep look into COVID-19 severity through dynamic changes in blood cytokine levels

DA Kleymenov, EN Bykonia, LI Popova… - Frontiers in …, 2021 - frontiersin.org
An excessive inflammatory response to SARS-CoV-2 is thought to be a major cause of
disease severity and mortality in patients with COVID-19. Longitudinal analysis of cytokine …

[HTML][HTML] Advances in COVID-19: the virus, the pathogenesis, and evidence-based control and therapeutic strategies

G Zhou, S Chen, Z Chen - Frontiers of medicine, 2020 - Springer
Since the outbreak of the COVID-19 pandemic in early December 2019, 81 174 confirmed
cases and 3242 deaths have been reported in China as of March 19, 2020. The Chinese …

[PDF][PDF] Coronavirus-19 (SARS-CoV-2) induces acute severe lung inflammation via IL-1 causing cytokine storm in COVID-19: a promising inhibitory strategy

P Conti, A Caraffa, CE Gallenga, R Ross… - J Biol Regul Homeost …, 2020 - researchgate.net
SARS-Cov-2 infection causes local and systemic inflammation mediated by pro-
inflammatory cytokines and COX-2 eicosanoid products with metabolic dysfunction and …

[HTML][HTML] Mechanistic insights into the immune pathophysiology of COVID-19; an in-depth review

A Shafqat, S Shafqat, SA Salameh, J Kashir… - Frontiers in …, 2022 - frontiersin.org
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2), which causes
coronavirus-19 (COVID-19), has caused significant morbidity and mortality globally. In …