Cytokines induced during influenza virus infection

T Betakova, A Kostrabova, V Lachova… - Current …, 2017 - ingentaconnect.com
Influenza A virus is one of the major human pathogens. The influenza infection can pass out
without any subclinical symptoms or infestation can appear in upper respiratory tract as well …

[PDF][PDF] The role of cytokines in the immune response to influenza A virus infection

T Sladkova, F Kostolansky - Acta virologica, 2006 - researchgate.net
Influenza A virus is one of the most important causes of respiratory tract diseases. It
replicates in epithelial cells and leukocytes resulting in the production of immune mediators …

Immunomodulatory therapy for severe influenza

I Darwish, S Mubareka, WC Liles - Expert review of anti-infective …, 2011 - Taylor & Francis
Influenza A virus is a significant cause of morbidity and mortality worldwide. Severe
influenza is recognized as a clinical syndrome, characterized by hyperinduction of …

Profiles of cytokine and chemokine gene expression in human pulmonary epithelial cells induced by human and avian influenza viruses

WY Lam, ACM Yeung, IMT Chu, PKS Chan - Virology journal, 2010 - Springer
Influenza pandemic remains a serious threat to human health. In this study, the repertoire of
host cellular cytokine and chemokine responses to infections with highly pathogenic avian …

Influenza (“Bird Flu”), inflammation and anti-inflammatory/analgesic drugs

KD Rainsford - Inflammopharmacology, 2006 - Springer
The spectre of an influenza pandemic is being widely mooted. Most of the strategies
explored to date for controlling or treating the condition have centred on controlling the …

Defense against influenza A virus infection: essential role of the chemokine system

A Kaufmann, R Salentin, RG Meyer, D Bussfeld… - Immunobiology, 2001 - Elsevier
Monocytes/macrophages are highly susceptible to an infection with influenza A virus. After
infection, de novo virus protein synthesis is detectable but rapidly interrupted before …

Confronting the next influenza pandemic with anti‐inflammatory and immunomodulatory agents: why they are needed and how they might work

DS Fedson - Influenza and other respiratory viruses, 2009 - Wiley Online Library
Despite the best efforts of influenza scientists, companies and health officials to prepare for
the next pandemic, most of the world's people will not have access to affordable supplies of …

The inflammatory response triggered by Influenza virus: a two edged sword

LP Tavares, MM Teixeira, CC Garcia - Inflammation research, 2017 - Springer
Influenza A virus (IAV) is a relevant respiratory tract pathogen leading to a great number of
deaths and hospitalizations worldwide. Secondary bacterial infections are a very common …

The cytokine storm of severe influenza and development of immunomodulatory therapy

Q Liu, Y Zhou, Z Yang - Cellular & molecular immunology, 2016 - nature.com
Severe influenza remains unusual in its virulence for humans. Complications or ultimately
death arising from these infections are often associated with hyperinduction of …

The role of cytokine responses during influenza virus pathogenesis and potential therapeutic options

JR Teijaro - Influenza Pathogenesis and Control-Volume II, 2014 - Springer
Aberrant pulmonary immune responses are linked to the pathogenesis of multiple human
respiratory viral infections. Elevated cytokine and chemokine production “cytokine storm” …