[HTML][HTML] Cytokine storm in COVID-19:“when you come out of the storm, you won't be the same person who walked in”

V Castelli, A Cimini, C Ferri - Frontiers in immunology, 2020 - frontiersin.org
In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

[HTML][HTML] Cytokines and chemokines in SARS-CoV-2 infections—therapeutic strategies targeting cytokine storm

A Pum, M Ennemoser, T Adage, AJ Kungl - Biomolecules, 2021 - mdpi.com
The recently identified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
virus, the cause of coronavirus disease (COVID-19) and the associated ongoing pandemic …

SARS-CoV-2 infection: The role of cytokines in COVID-19 disease

VJ Costela-Ruiz, R Illescas-Montes… - Cytokine & growth factor …, 2020 - Elsevier
COVID-19 disease, caused by infection with SARS-CoV-2, is related to a series of
physiopathological mechanisms that mobilize a wide variety of biomolecules, mainly …

[HTML][HTML] Cytokine storm in COVID-19—immunopathological mechanisms, clinical considerations, and therapeutic approaches: the REPROGRAM consortium position …

S Bhaskar, A Sinha, M Banach, S Mittoo… - Frontiers in …, 2020 - frontiersin.org
Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

[HTML][HTML] COVID-19: in the eye of the cytokine storm

R De la Rica, M Borges, M Gonzalez-Freire - Frontiers in immunology, 2020 - frontiersin.org
The dysregulated release of cytokines has been identified as one of the key factors behind
poorer outcomes in COVID-19. This “cytokine storm” produces an excessive inflammatory …

[HTML][HTML] Immunopathogenesis and treatment of cytokine storm in COVID-19

JS Kim, JY Lee, JW Yang, KH Lee, M Effenberger… - Theranostics, 2021 - ncbi.nlm.nih.gov
Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

[HTML][HTML] Cytokine storm intervention in the early stages of COVID-19 pneumonia

X Sun, T Wang, D Cai, Z Hu, H Liao, L Zhi, H Wei… - Cytokine & growth factor …, 2020 - Elsevier
Clinical intervention in patients with corona virus disease 2019 (COVID-19) has
demonstrated a strong upregulation of cytokine production in patients who are critically ill …

Deciphering the COVID‐19 cytokine storm: systematic review and meta‐analysis

R Mulchandani, T Lyngdoh… - European journal of …, 2021 - Wiley Online Library
Introduction The coronavirus pandemic has affected more than 20 million people so far.
Elevated cytokines and suppressed immune responses have been hypothesized to set off a …

The roles of critical pro‐inflammatory cytokines in the drive of cytokine storm during SARS‐CoV‐2 infection

MS Qudus, M Tian, S Sirajuddin, S Liu… - Journal of Medical …, 2023 - Wiley Online Library
In patients with severe COVID‐19, acute respiratory distress syndrome (ARDS), multiple
organ dysfunction syndrome (MODS), and even mortality can result from cytokine storm …

The pro-inflammatory cytokines in COVID-19 pathogenesis: What goes wrong?

D Darif, I Hammi, A Kihel, IEI Saik, F Guessous… - Microbial …, 2021 - Elsevier
The outbreak of coronavirus disease 2019 (COVID-19), caused by Severe Acute Respiratory
Syndrome Coronavirus 2 (SARS-CoV-2) infection, has emerged in China in December 2019 …