[HTML][HTML] Recent insight into SARS-CoV2 immunopathology and rationale for potential treatment and preventive strategies in COVID-19

S Lega, S Naviglio, S Volpi, A Tommasini - Vaccines, 2020 - mdpi.com
As the outbreak of the new coronavirus (SARS-CoV-2) infection is spreading globally, great
effort is being made to understand the disease pathogenesis and host factors that …

Severe COVID-19: immunosuppression or hyperinflammation?

Y Liu, Y Li, D Xu, J Zhang, Z Peng - Shock, 2021 - journals.lww.com
The ongoing coronavirus disease 2019 (COVID-19) pandemic has swept over the world and
causes thousands of deaths. Although the clinical features of COVID-19 become much …

Role for anti-cytokine therapies in severe coronavirus disease 2019

LF Buckley, GF Wohlford, C Ting… - Critical care …, 2020 - journals.lww.com
Objectives: The causative agent for coronavirus disease 2019, severe acute respiratory
syndrome coronavirus 2, appears exceptional in its virulence and immunopathology. In …

The unleashing of the immune system in COVID-19 and sepsis: the calm before the storm?

S Bellinvia, CJ Edwards, M Schisano, P Banfi… - Inflammation …, 2020 - Springer
The novel coronavirus disease 2019 (COVID-19) pandemic caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) is sorely testing health care systems and …

Altered cytokine levels and immune responses in patients with SARS-CoV-2 infection and related conditions

R Noroozi, W Branicki, K Pyrc, PP Łabaj, E Pospiech… - Cytokine, 2020 - Elsevier
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a global
pandemic in early 2020. The infection has been associated with a wide range of clinical …

Macrophage responses associated with COVID-19: A pharmacological perspective

GW Booz, R Altara, AH Eid, Z Wehbe, S Fares… - European Journal of …, 2020 - Elsevier
COVID-19 has caused worldwide death and economic destruction. The pandemic is the
result of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), which has …

The amount of cytokine-release defines different shades of Sars-Cov2 infection

S Bindoli, M Felicetti, P Sfriso… - … Biology and Medicine, 2020 - journals.sagepub.com
The recent outbreak of coronavirus disease (COVID 19), spreading from China all around
the world in early 2020, has led scientists to investigate the immuno-mediated mechanisms …

SARS-CoV-2: a storm is raging

SF Pedersen, YC Ho - The Journal of clinical investigation, 2020 - Am Soc Clin Investig
The pandemic coronavirus infectious disease (COVID-19), caused by severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2), is rapidly spreading across the globe. In …

[HTML][HTML] Profile of circulatory cytokines and chemokines in human coronaviruses: a systematic review and meta-analysis

A Zawawi, AY Naser, H Alwafi, F Minshawi - Frontiers in Immunology, 2021 - frontiersin.org
Background SARS, MERS, and COVID-19 share similar characteristics. For instance, the
genetic homology of SARS-CoV-2 compared to SARS-CoV and MERS-CoV is 80% and …

COVID‐19: Consider IL‐6 receptor antagonist for the therapy of cytokine storm syndrome in SARS‐CoV‐2 infected patients

C Chakraborty, AR Sharma… - Journal of medical …, 2020 - Wiley Online Library
COVID‐19 leads to mortality of several patients and the cytokine storm is reportedly critical
in the patients. To reduce the cytokine storm, we would like to propose the interleukin (IL) 6 …