As of May 11, 2020, coronavirus disease 2019 (Covid-19) has been confirmed in 4 152 670
people worldwide, carrying a mortality of approximately 6.8%, 1 compared with a mortality …

Haemophagocytic lymphohistiocytosis, which is frequently described as a'cytokine storm', is
characterised by fulminant, fatal hypercytokinemia with multiple organ failure (2). This …

Cytokine storm is an acute hyperinflammatory response that may be responsible for critical
illness in many conditions including viral infections, cancer, sepsis, and multi-organ failure …

Cytokine storm syndrome (CSS) is a critical clinical condition induced by a cascade of
cytokine activation, characterized by overwhelming systemic inflammation …

Abstract Severe coronavirus disease 2019 (COVID-19) is characterized by systemic hyper-
inflammation, acute respiratory distress syndrome, and multiple organ failure. Cytokine …

Correspondence 26 www. thelancet. com/infection Vol 21 January 2021 acceleration of
cases seen in the eastern region (99 cases per 100 000). Per 100 000 population, Mecca …

Highlights•Clinical picture generally manifests as “overlap syndrome” and leads to vicious
circle.•Early identification of rising cytokine storm and multilevel course of treatment is …

In December 2019, a novel coronavirus, COVID-19, was discovered to be the causal agent
of a severe respiratory infection named SARS-CoV-2, and it has since been recognized …

As of January, 2021, nearly 2-million deaths worldwide have been attributed to COVID-19,
which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). Much …

Abstract Coronavirus disease 2019 (COVID-19), caused by the virus designated as severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has spread widely throughout the …