In the present study, cyclosporine A (CsA) was successfully incorporated into cationic
chitosan nanoparticles by spray-drying method aiming ocular application. Physicochemical …

Present limitations in the management of extraocular diseases include the inability to
provide long-term extraocular drug delivery without compromising intraocular structures …

The present study was aimed at investigation of thiolated derivative of chitosan for
development of microspheres for ocular delivery of the antiviral agent, acyclovir. N-Acetyl …

The aim of the present investigation was to evaluate the potential use of chitosan
microspheres for ocular delivery of acyclovir. The topical application of acyclovir as eye …

Acyclovir-loaded chitosan nanoparticles for ocular delivery Page 1 Asian Journal of
Pharmaceutics - October-December 2010 220 INTRODUCTION Acyclovir is an antiviral …

Ocular chitosan films were prepared in order to prolong ocular delivery of cyclosporine A.
The mucoadhesive films were prepared using the solvent casting evaporation method. A 2 4 …

The aim of this study was to develop cyclosporine A (CsA) loaded solid lipid nanoparticles
(SLN) associated with chitosan (CS), to improve interaction and internalization in corneal …

Cyclosporine-loaded solid lipid nanoparticles were prepared according to the coacervation
method: various stabilizers were used in order to obtain nanoparticles with different surface …

Cyclosporine A loaded poly (lactide-co-glycolide) nanoparticles coated with chitosan were
prepared using the o/w emulsification solvent evaporation method. A 23 full factorial design …

For the treatment of ocular keratitis acyclovir, as a highly specific inhibitor of herpes virus
replication, is applied topically into the eye. The objective of this study was to design and …