Despite the successful identification of several relevant genomic loci, the underlying
molecular mechanisms of schizophrenia remain largely unclear. We developed a …

Genetic analysis is currently offering glimpses into molecular mechanisms underlying such
neuropsychiatric disorders as schizophrenia, bipolar disorder and autism. After years of …

Numerous studies have examined gene expression profiles in post-mortem human brain
samples from individuals with schizophrenia compared with healthy controls, to gain insight …

Over 100 genetic loci harbor schizophrenia-associated variants, yet how these variants
confer liability is uncertain. The CommonMind Consortium sequenced RNA from …

Genome-wide association studies (GWAS) have identified a large number of gene variants
associated with schizophrenia, but these variants explain only a small portion of the …

We performed integrated gene coexpression network analysis on two large microarray-
based brain gene expression data sets generated from the prefrontal cortex obtained post …

Abstract 16p11. 2 and 22q11. 2 Copy Number Variants (CNVs) confer high risk for Autism
Spectrum Disorder (ASD), schizophrenia (SZ), and Attention-Deficit-Hyperactivity-Disorder …

Schizophrenia is a psychiatric disorder whose pathophysiology is largely unknown. It has a
heritability of 60-80%, much of which is attributable to common risk alleles, suggesting …

Schizophrenia is a psychiatric disorder with onset in late adolescence and unclear etiology
characterized by both positive and negative symptoms, as well as cognitive deficits. To …

The genetic basis of schizophrenia has been a hotly debated research topic for decades, yet
recent studies, especially in the past year, have confirmed genetics as the major cause of …