Requirement of LaeA for secondary metabolism and sclerotial production in Aspergillus flavus

SP Kale, L Milde, MK Trapp, JC Frisvad… - Fungal Genetics and …, 2008 - Elsevier
The nuclear regulator LaeA has been shown to govern production of multiple secondary
metabolites in Aspergillus nidulans and Aspergillus fumigatus. Herein we examine the role …

Overview on aflatoxins and oxidative stress

DE Marin, I Taranu - Toxin Reviews, 2012 - Taylor & Francis
Aflatoxins are naturally occurring mycotoxins that are produced by many species of
Aspergillus, a fungus, mainly by Aspergillus flavus and Aspergillus parasiticus. Aflatoxins …

Characterization of experimentally induced, nonaflatoxigenic variant strains of Aspergillus parasiticus

SP Kale, JW Cary, D Bhatnagar… - Applied and …, 1996 - Am Soc Microbiol
Six previously isolated, nonaflatoxigenic variants of Aspergillus parasiticus, designated sec
mutants, were characterized morphologically by electron microscopy, biochemically by …

[图书][B] Aflatoxin biosynthetic pathway and pathway genes

J Yu, KC Ehrlich - 2011 - aspergillus.org.uk
Among the over 185 known species within the genus Aspergillus, Aspergillus flavus is the
most economically important because it produces the toxic and carcinogenic aflatoxins. Its …

Environmental influences on maize-Aspergillus flavus interactions and aflatoxin production

JC Fountain, BT Scully, X Ni, RC Kemerait… - Frontiers in …, 2014 - frontiersin.org
Since the early 1960s, the fungal pathogen Aspergillus flavus (Link ex Fr.) has been the
focus of intensive research due to the production of carcinogenic and highly toxic secondary …

The production of aflatoxin B1 or G1 by Aspergillus parasiticus at various combinations of temperature and water activity is related to the ratio of aflS to aflR …

M Schmidt-Heydt, CE Rüfer, A Abdel-Hadi, N Magan… - Mycotoxin …, 2010 - Springer
The influence of varying combinations of water activity (aw) and temperature on growth,
aflatoxin biosynthesis and afl R/afl S expression of Aspergillus parasiticus was analysed in …

Aspergillus flavus VelB acts distinctly from VeA in conidiation and may coordinate with FluG to modulate sclerotial production

PK Chang, LL Scharfenstein, P Li, KC Ehrlich - Fungal Genetics and …, 2013 - Elsevier
Abstract The proteins VeA, VelB and LaeA of Aspergillus nidulans form a heterotrimeric
complex (the velvet complex) in the dark to coordinate sexual development and production …

A beta-glucuronidase reporter gene construct for monitoring aflatoxin biosynthesis in Aspergillus flavus

JE Flaherty, MA Weaver, GA Payne… - Applied and …, 1995 - Am Soc Microbiol
Aflatoxins are toxic and carcinogenic secondary metabolites produced by the fungi
Aspergillus flavus and A. parasiticus. Current research is directed at the elimination of these …

Complex regulation of the aflatoxin biosynthesis gene cluster of Aspergillus flavus in relation to various combinations of water activity and temperature

M Schmidt-Heydt, A Abdel-Hadi, N Magan… - International journal of …, 2009 - Elsevier
A microarray analysis was performed to study the effect of varying combinations of water
activity and temperature on the activation of aflatoxin biosynthesis genes in …

Understanding the genetics of regulation of aflatoxin production and Aspergillus flavus development

D Bhatnagar, JW Cary, K Ehrlich, J Yu, TE Cleveland - Mycopathologia, 2006 - Springer
Aflatoxins are polyketide-derived, toxic, and carcinogenic secondary metabolites produced
primarily by two fungal species, Aspergillus flavus and A. parasiticus, on crops such as corn …