Pathogenesis of wild-type-like rhesus cytomegalovirus strains following oral exposure of immune-competent rhesus macaques

Y Yue, WLW Chang, J Li, N Nguyen… - Journal of …, 2022 - Am Soc Microbiol
Rhesus cytomegalovirus (RhCMV) infection of rhesus macaques (Macaca mulatta) is a
valuable nonhuman primate model of human CMV (HCMV) persistence and pathogenesis …

Rhesus cytomegalovirus: A nonhuman primate model for the study of human cytomegalovirus

Y Yue, PA Barry - Advances in virus research, 2008 - Elsevier
Human cytomegalovirus (HCMV), a member of an ancient family of viruses (Herpesviridae),
has acquired the capacity to maintain a lifelong persistent infection within an …

Rhesus monkeys for a nonhuman primate model of cytomegalovirus infections

HL Itell, A Kaur, JD Deere, PA Barry… - Current opinion in virology, 2017 - Elsevier
Highlights•Nonhuman primate (NHP) CMVs are most closely related to human CMV
(HCMV).•Rhesus CMV (RhCMV) bears numerous genomic and functional similarities to …

In vitro and in vivo characterization of a recombinant rhesus cytomegalovirus containing a complete genome

H Taher, E Mahyari, C Kreklywich, LS Uebelhoer… - PLoS …, 2020 - journals.plos.org
Cytomegaloviruses (CMVs) are highly adapted to their host species resulting in strict
species specificity. Hence, in vivo examination of all aspects of CMV biology employs animal …

Open reading frames carried on UL/b′ are implicated in shedding and horizontal transmission of rhesus cytomegalovirus in rhesus monkeys

KL Oxford, L Strelow, Y Yue, WLW Chang… - Journal of …, 2011 - Am Soc Microbiol
Implicit with the use of animal models to test human cytomegalovirus (HCMV) vaccines is the
assumption that the viral challenge of vaccinated animals reflects the anticipated virus-host …

Cross-species rhesus cytomegalovirus infection of cynomolgus macaques

BJ Burwitz, D Malouli, BN Bimber, JS Reed… - PLoS …, 2016 - journals.plos.org
Cytomegaloviruses (CMV) are highly species-specific due to millennia of co-evolution and
adaptation to their host, with no successful experimental cross-species infection in primates …

Examining the species-specificity of rhesus macaque cytomegalovirus (RhCMV) in cynomolgus macaques

AK Marsh, AP Ambagala, CT Perciani, JNH Russell… - PLoS …, 2015 - journals.plos.org
Cytomegalovirus (CMV) is a highly species-specific virus that has co-evolved with its host
over millions of years and thus restricting cross-species infection. To examine the extent to …

Pathogenesis of experimental rhesus cytomegalovirus infection

KM Lockridge, G Sequar, SS Zhou, Y Yue… - Journal of …, 1999 - Am Soc Microbiol
Human cytomegalovirus (HCMV) establishes and maintains a lifelong persistence following
infection in an immunocompetent host. The determinants of a stable virus-host relationship …

Patterns of acute rhesus cytomegalovirus (RhCMV) infection predict long-term RhCMV infection

BT Assaf, KG Mansfield, SV Westmoreland… - Journal of …, 2012 - Am Soc Microbiol
We previously reported that long-term rhesus cytomegalovirus (RhCMV) excretion in
infected macaques was related to UL/b′ coding content. Acute biopsy specimens of the …

Natural history of postnatal rhesus cytomegalovirus shedding by dams and acquisition by infant rhesus monkeys

A Kaur, HL Itell, EP Ehlinger, V Varner, S Gantt… - PLoS …, 2018 - journals.plos.org
Background Human infants frequently acquire human cytomegalovirus (HCMV) through
breastfeeding, resulting in persistent high-level viral shedding in saliva and urine and …