Alternative mRNA splicing is a rich source of transcript diversity in eukaryotic cells with
broad roles in development and disease. Systems-wide experimental methods have started …

Alternative splicing of mRNA precursors provides an important means of genetic control and
is a crucial step in the expression of most genes. Alternative splicing markedly affects human …

Alternative splicing plays critical roles in differentiation, development, and disease and is a
major source for protein diversity in higher eukaryotes. Analysis of alternative splicing …

Alternative splicing of mRNA precursors allows the synthesis of multiple mRNAs from a
single primary transcript, significantly expanding the information content and regulatory …

Alternative splicing is a process to differentially link exon regions in a single precursor
mRNA to produce two or more different mature mRNAs, a strategy frequently used by higher …

The first wave of bioinformatic studies that followed genome and complementary DNA
sequencing projects revealed that alternative splicing of messenger RNA precursors (pre …

With recent advances in microarrays and sequencing it is now relatively straightforward to
compare pre-mRNA splicing patterns in different cellular conditions on a genome-wide …

Alternative splicing plays a prevalent role in generating functionally diversified proteomes
from genomes with a more limited repertoire of protein-coding genes. Alternative splicing is …

Alternative splicing is a process by which multiple messenger RNAs (mRNAs) are generated
from a single pre-mRNA, resulting in functionally distinct protein products. This is …

Splicing of precursor mRNAs (pre-mRNA) is an important step during eukaryotic gene
expression. The identification of the actual splice sites and the proper removal of introns are …