[HTML][HTML] Magnitude and dynamics of the T-cell response to SARS-CoV-2 infection at both individual and population levels

TM Snyder, RM Gittelman, M Klinger, DH May… - MedRxiv, 2020 - ncbi.nlm.nih.gov
T cells are involved in the early identification and clearance of viral infections and also
support the development of antibodies by B cells. This central role for T cells makes them a …

Presence of SARS-CoV-2-reactive T cells in COVID-19 patients and healthy donors

J Braun, L Loyal, M Frentsch, D Wendisch, P Georg… - MedRxiv, 2020 - medrxiv.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused a rapidly
unfolding pandemic, overwhelming health care systems worldwide 1. Clinical manifestations …

Multimodal single-cell datasets characterize antigen-specific CD8+ T cells across SARS-CoV-2 vaccination and infection

B Zhang, R Upadhyay, Y Hao, MI Samanovic… - Nature …, 2023 - nature.com
The immune response to SARS-CoV-2 antigen after infection or vaccination is defined by
the durable production of antibodies and T cells. Population-based monitoring typically …

Phenotype and kinetics of SARS-CoV-2–specific T cells in COVID-19 patients with acute respiratory distress syndrome

D Weiskopf, KS Schmitz, MP Raadsen, A Grifoni… - Science …, 2020 - science.org
SARS-CoV-2 has been identified as the causative agent of a global outbreak of respiratory
tract disease (COVID-19). In some patients, the infection results in moderate to severe acute …

[HTML][HTML] Targets of T cell responses to SARS-CoV-2 coronavirus in humans with COVID-19 disease and unexposed individuals

A Grifoni, D Weiskopf, SI Ramirez, J Mateus, JM Dan… - Cell, 2020 - cell.com
Understanding adaptive immunity to SARS-CoV-2 is important for vaccine development,
interpreting coronavirus disease 2019 (COVID-19) pathogenesis, and calibration of …

A regulatory T cell signature distinguishes the immune landscape of COVID-19 patients from those with other respiratory infections

SC Vick, M Frutoso, F Mair, AJ Konecny, E Greene… - Science …, 2021 - science.org
Despite recent studies of immunity to severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2), little is known about how the immune response against SARS-CoV-2 differs …

[HTML][HTML] Imbalance of regulatory and cytotoxic SARS-CoV-2-reactive CD4+ T cells in COVID-19

BJ Meckiff, C Ramírez-Suástegui, V Fajardo, SJ Chee… - Cell, 2020 - cell.com
The contribution of CD4+ T cells to protective or pathogenic immune responses to SARS-
CoV-2 infection remains unknown. Here, we present single-cell transcriptomic analysis of> …

SARS-CoV-2 genome-wide T cell epitope mapping reveals immunodominance and substantial CD8+ T cell activation in COVID-19 patients

SK Saini, DS Hersby, T Tamhane, HR Povlsen… - Science …, 2021 - science.org
T cells are important for effective viral clearance, elimination of virus-infected cells, and long-
term disease protection. To examine the full spectrum of CD8+ T cell immunity in COVID-19 …

[HTML][HTML] COVID-19 immune signatures reveal stable antiviral T cell function despite declining humoral responses

A Bonifacius, S Tischer-Zimmermann, AC Dragon… - Immunity, 2021 - cell.com
Cellular and humoral immunity to SARS-CoV-2 is critical to control primary infection and
correlates with severity of disease. The role of SARS-CoV-2-specific T cell immunity, its …

T cells in COVID-19—united in diversity

L Swadling, MK Maini - Nature immunology, 2020 - nature.com
T cells in COVID-19 — united in diversity | Nature Immunology Skip to main content Thank
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