Heterotopic ossification (HO), the abnormal formation of true marrow-containing bone within
extraskeletal soft tissues, is a serious bony disorder that may be either acquired or …

Put most simply, heterotopic ossification (HO) is the abnormal formation of bone at
extraskeletal sites. HO can be classified into two main subtypes, genetic and acquired …

Heterotopic ossification (HO) is a debilitating condition defined by the de novo development
of bone within non-osseous soft tissues, and can be either hereditary or acquired. The …

Heterotopic ossification is characterized by the formation of normal bone at ectopic soft‐
tissue locations. Regardless of the etiology of heterotopic ossification, requisite pathogenetic …

Cells with osteogenic potential can be found in a variety of tissues. Here we show that
circulating osteogenic precursor (COP) cells, a bone marrow-derived type I …

Background: Fibrodysplasia ossificans progressiva is a rare genetic disorder of ectopic
skeletogenesis associated with dysregulation of bone morphogenetic protein (BMP) …

Background Heterotopic ossification (HO), either acquired (aHO) or hereditary, such as
fibrodysplasia ossificans progressiva (FOP), is a serious condition without effective …

Background: Individuals who have fibrodysplasia ossificans progressiva develop an ectopic
skeleton because of genetic dysregulation of bone morphogenetic protein (BMP) signaling …

Heterotopic ossification (HO) is the formation of marrow‐containing bone outside of the
normal skeleton. Acquired HO following traumatic events is a common and costly clinical …

Heterotopic ossification (HO) is a pathological condition of abnormal bone formation in soft
tissue. Three factors have been proposed as required to induce HO:(a) osteogenic precursor …