Molecular mechanisms of pulmonary fibrogenesis and its progression to lung cancer: a review

T Kinoshita, T Goto - International journal of molecular sciences, 2019 - mdpi.com
Idiopathic pulmonary fibrosis (IPF) is defined as a specific form of chronic, progressive
fibrosing interstitial pneumonia of unknown cause, occurring primarily in older adults, and …

Overview of pulmonary fibrosis

FHY Green - Chest, 2002 - Elsevier
Pulmonary fibrosis is a component of over 200 interstitial lung diseases. Some have known
etiologies, however, for many diseases, the etiology remains unknown or obscure. This brief …

Chemokine/cytokine cocktail in idiopathic pulmonary fibrosis

C Agostini, C Gurrieri - Proceedings of the American Thoracic …, 2006 - atsjournals.org
Idiopathic pulmonary fibrosis (IPF) is a progressive and irreversible fibrosing lung disease of
unknown etiology and with an unfavorable outcome, leading ultimately to death due to …

Antifibrotic therapy for the treatment of pulmonary fibrosis

JA Lasky, LA Ortiz - The American journal of the medical sciences, 2001 - Elsevier
Fibroproliferative lung disease is prevalent and associated with high mortality. The
pathogenesis of fibrotic lung disease involves inflammation, mesenchymal cell proliferation …

Spectrum of fibrotic lung diseases

M Wijsenbeek, V Cottin - New England Journal of Medicine, 2020 - Mass Medical Soc
Pulmonary Fibrotic Diseases This review covers fibrotic pulmonary diseases. Although
idiopathic pulmonary fibrosis is very common, the review focuses mainly on fibrotic diseases …

Metalloproteinases in idiopathic pulmonary fibrosis

RCA Dancer, AM Wood… - European Respiratory …, 2011 - Eur Respiratory Soc
In this article, we outline the current state of knowledge about the balance between collagen
production and degradation in idiopathic pulmonary fibrosis (IPF). The dysregulated action …

Molecular biomarkers in idiopathic pulmonary fibrosis: state of the art and future directions

A Stainer, P Faverio, S Busnelli, M Catalano… - International Journal of …, 2021 - mdpi.com
Idiopathic pulmonary fibrosis (IPF), the most lethal form of interstitial pneumonia of unknown
cause, is associated with a specific radiological and histopathological pattern (the so-called …

An official American Thoracic Society workshop report: use of animal models for the preclinical assessment of potential therapies for pulmonary fibrosis

RG Jenkins, BB Moore, RC Chambers… - American journal of …, 2017 - atsjournals.org
Numerous compounds have shown efficacy in limiting development of pulmonary fibrosis
using animal models, yet few of these compounds have replicated these beneficial effects in …

[HTML][HTML] The treatment of idiopathic pulmonary fibrosis

HV Woodcock, TM Maher - F1000prime reports, 2014 - ncbi.nlm.nih.gov
Idiopathic pulmonary fibrosis (IPF) is a progressive and invariably fatal disease with a
median survival of less than three years from diagnosis. The last decade has seen an …

Emerging drug delivery strategies for idiopathic pulmonary fibrosis treatment

M Ghumman, D Dhamecha, A Gonsalves… - European Journal of …, 2021 - Elsevier
Idiopathic pulmonary fibrosis (IPF) is a debilitating and fatal condition that causes severe
scarring of the lungs. While the pathogenesis of IPF continues to be extensively studied and …