Dynamic changes in serum IL-6, IL-8, and IL-10 are associated with the outcome of patients with severe COVID-19 in ICU

J Li, L Rong, R Cui, J Feng, Y Jin, Y Yu, X Chen, R Xu - 2020 - researchsquare.com
Background: Biomarkers that would help prognosticate outcomes and guide treatment of
patients with severe coronavirus disease 2019 (COVID-19) are currently required. We aimed …

Cytokines and their relationship with the severity and prognosis of coronavirus disease 2019 (COVID-19): a retrospective cohort study

QQ Liu, A Cheng, Y Wang, H Li, L Hu, X Zhao… - BMJ open, 2020 - bmjopen.bmj.com
Objective To delineate the characteristics and clinical significance of plasma inflammatory
cytokines altered in COVID-19. Design Retrospective, single-centre cohort study. Setting …

Deciphering the balance of IL-6/IL-10 cytokines in severe to critical COVID-19 patients

MB Azaiz, AB Jemaa, W Sellami, C Romdhani… - Immunobiology, 2022 - Elsevier
The severity of COVID-19 is largely determined by the inflammatory response, a “Cytokine
storm,” that involves both pro-and anti-inflammatory cytokines. In the current study we …

Profiling serum cytokines in COVID-19 patients reveals IL-6 and IL-10 are disease severity predictors

H Han, Q Ma, C Li, R Liu, L Zhao, W Wang… - Emerging microbes & …, 2020 - Taylor & Francis
Since the outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, it has rapidly
spread across many other countries. While the majority of patients were considered mild …

Interleukine-6 in critically ill COVID-19 patients: A retrospective analysis

J Gorham, A Moreau, F Corazza, L Peluso… - PLoS …, 2020 - journals.plos.org
Introduction Coronavirus disease 2019 (COVID-19) appeared in China in December 2019
and has spread around the world. High Interleukin-6 (IL-6) levels in COVID-19 patients …

Dynamic interleukin-6 level changes as a prognostic indicator in patients with COVID-19

Z Liu, J Li, D Chen, R Gao, W Zeng, S Chen… - Frontiers in …, 2020 - frontiersin.org
Background Interleukin-6 (IL-6), a proinflammatory cytokine, has been reported to be
associated with disease severity and mortality in patients with coronavirus disease 2019 …

Time evolution of cytokine profiles associated with mortality in COVID-19 hospitalized patients

L Sanchez-de Prada, Ó Gorgojo-Galindo… - Frontiers in …, 2022 - frontiersin.org
Background High cytokine levels have been associated with severe COVID-19 disease.
Although many cytokine studies have been performed, not many of them include …

[HTML][HTML] Cytokine profile in plasma of severe COVID-19 does not differ from ARDS and sepsis

JG Wilson, LJ Simpson, AM Ferreira, A Rustagi… - JCI insight, 2020 - ncbi.nlm.nih.gov
BACKGROUND Elevated levels of inflammatory cytokines have been associated with poor
outcomes among COVID-19 patients. It is unknown, however, how these levels compare …

[PDF][PDF] Association of interleukin-6 levels with morbidity and mortality in patients with coronavirus disease 2019 (COVID-19)

J Zhou, W He, J Liang, L Wang, X Yu, M Bao, H Liu - Jpn J Infect Dis, 2021 - niid.go.jp
The prognostic value of interleukin-6 in COVID-19 needs to be clarified. In this retrospective
study, COVID-19 patients treated in Renmin Hospital of Wuhan University from Jan 7 to Feb …

[HTML][HTML] A score combining early detection of cytokines accurately predicts COVID-19 severity and intensive care unit transfer

C Nagant, F Ponthieux, J Smet, N Dauby… - International Journal of …, 2020 - Elsevier
Objectives We aimed to explore cytokine profile in patients as it relates to Coronavirus
Disease 2019 (COVID-19) severity, and to establish a predictive cytokine score to …