[HTML][HTML] CircRNA hsa_circ_0110102 inhibited macrophage activation and hepatocellular carcinoma progression via miR-580-5p/PPARα/CCL2 pathway

X Wang, W Sheng, T Xu, J Xu, R Gao… - Aging (Albany NY), 2021 - ncbi.nlm.nih.gov
Circular RNAs (circRNAs) have critical regulatory roles in tumor biology. However, their
contributions in hepatocellular carcinoma (HCC) still remain enigmatic. The present study …

[HTML][HTML] Up-regulation of circRNA-0003528 promotes mycobacterium tuberculosis associated macrophage polarization via down-regulating miR-224-5p, miR-324-5p …

Z Huang, F Yao, J Liu, J Xu, Y Guo, R Su, Q Luo… - Aging (Albany …, 2020 - ncbi.nlm.nih.gov
Background: In this study, we selected several candidate miRNAs to study their possible
relationships with tuberculosis. Results: The expression of hsa_circ_0003528 was …

[HTML][HTML] circRNA mediates silica-induced macrophage activation via HECTD1/ZC3H12A-dependent ubiquitination

Z Zhou, R Jiang, X Yang, H Guo, S Fang, Y Zhang… - Theranostics, 2018 - ncbi.nlm.nih.gov
Rationale: Phagocytosis of silicon dioxide (SiO 2) into lung cells causes an inflammatory
cascade that results in fibroblast proliferation and migration, followed by fibrosis. Circular …

[HTML][HTML] circRNA. 33186 contributes to the pathogenesis of osteoarthritis by sponging miR-127-5p

Z Zhou, G Huang, Q Fu, B Han, J Lu, A Chen, L Zhu - Molecular Therapy, 2019 - cell.com
Osteoarthritis (OA), the most prevalent age-related joint disorder, is characterized by chronic
inflammation, progressive articular cartilage destruction, and subchondral bone sclerosis …

[HTML][HTML] Circular RNA circBbs9 promotes PM2. 5-induced lung inflammation in mice via NLRP3 inflammasome activation

M Li, Q Hua, Y Shao, H Zeng, Y Liu, Q Diao… - Environment …, 2020 - Elsevier
Abstract Fine particulate matter (PM 2.5) is one of the most important components of
environmental pollutants, and is associated with pulmonary injury. However, the biological …

[HTML][HTML] hsa_circ_0068631 promotes breast cancer progression through c-Myc by binding to EIF4A3

X Wang, M Chen, L Fang - Molecular Therapy-Nucleic Acids, 2021 - cell.com
Breast cancer (BC) is one of the most common malignancies among women worldwide with
a high incidence of recurrence and metastasis. In this study, we demonstrate that …

The down-regulation of hsa_circ_0012919, the sponge for miR-125a-3p, contributes to DNA methylation of CD11a and CD70 in CD4+ T cells of systemic lupus …

C Zhang, X Wang, Y Chen, Z Wu, C Zhang… - Clinical …, 2018 - portlandpress.com
Background: Systemic lupus erythematous (SLE) is an autoimmune disease characterized
by the production of autoantibodies directed against various autoantigens. But the …

[HTML][HTML] circRNA_0000140 suppresses oral squamous cell carcinoma growth and metastasis by targeting miR-31 to inhibit Hippo signaling pathway

QS Peng, YN Cheng, WB Zhang, H Fan, QH Mao… - Cell Death & …, 2020 - nature.com
Oral squamous cell carcinoma (OSCC) is one of the most common malignancies and has a
poor prognosis. Circular RNA (circRNA) has been increasingly recognized as a crucial …

Downregulation of hsa_circ_0007534 restricts the proliferation and invasion of cervical cancer through regulating miR-498/BMI-1 signaling

X Rong, W Gao, X Yang, J Guo - Life sciences, 2019 - Elsevier
Aims Hsa_circ_0007534 has been reported to be a novel cancer-related circRNA affecting
multiple cancers. However, little is known about the role of hsa_circ_0007534 in cervical …

CircRNA hsa_circ_0004771 promotes esophageal squamous cell cancer progression via miR-339-5p/CDC25A axis

E Huang, J Fu, Q Yu, P Xie, Z Yang, H Ji, L Wang… - …, 2020 - Taylor & Francis
Aim: The role of circRNAs in esophageal squamous cell cancer (ESCC) remains unclear.
Materials & methods: Here we profiled six pair plasma circRNA in ESCC based on RNA …