Allergic diseases have reached epidemic proportions worldwide. An understanding of the
cellular and soluble mediators that are involved in allergic inflammatory responses not only …

Current therapies for asthma and allergy are relatively safe and effective at controlling
symptoms but do not change the chronic course of disease. There is no established method …

Immune modulation for treatment of allergic diseases aims to decrease the pathologic
immune response rather than to cause a return to an immunologically naive or unresponsive …

Advances in our understanding of allergic inflammation have led to the development of
several novel anti-inflammatory drugs that target specific aspects of the inflammatory …

The rising prevalence of allergies represents an increasing socioeconomic burden. A
detailed understanding of the immunological mechanisms that underlie the development of …

Abstract Purpose of Review The development of biological therapies has rapidly progressed
during the last few years, and major advances were reported for the treatment of allergic …

The specialties of allergy and clinical immunology have entered the era of precision
medicine with the stratification of diseases into distinct disease subsets, specific diagnoses …

Current asthma therapy is based on the use of adrenergic bronchodilator and anti-
inflammatory drugs the specificity, efficacy, duration of action, and safety of which have been …

Allergen immunotherapy is a form of therapeutic vaccination for established IgE-mediated
hypersensitivity to common allergen sources such as pollens, house dust mites and the …

Allergic rhinitis is an inflammatory disorder of the nasal mucosa, mediated by TH2
lymphocytes, which is linked to atopy and whose prevalence is increasing in association …