Older adults tend to over-activate regions throughout frontoparietal cortices and exhibit a
reduced range of functional modulation during WM task performance compared to younger …

Alteration of dynamic range of modulation to cognitive difficulty has been proposed as a
salient predictor of cognitive aging. Here, we examine in 171 adults (aged 20–94 years) the …

BOLD variability, which measures moment-to-moment fluctuations in brain signal, is
sensitive to age differences in cognitive performance. However, the effect of aging on BOLD …

Impairments in working memory (WM) are evident in both clinically diagnosed patients with
mild cognitive decline and older adults at risk, as indicated by lower scores on …

We aimed to identify brain functional correlates of working memory performance in aging, in
hopes of facilitating understanding of mechanisms that promote better versus worse working …

Individual differences in working memory (WM) performance have rarely been related to
individual differences in the functional responsivity of the WM brain network. By neglecting …

Effective cognitive performance often requires the allocation of additional neural resources
(ie blood-oxygen-level-dependent [BOLD] activation) as task demands increase, and this …

There is evidence that the neural response to increasing working memory (WM) load is
modulated by age and performance level. For a valid interpretation of these effects …

Introduction: Working memory (WM) and its blood-oxygen-level-dependent-related
parametric modulation under load decrease with age. Functional connectivity (FC) generally …

Working memory (WM) declines as we age and, because of its fundamental role in higher
order cognition, this can have highly deleterious effects in daily life. We investigated whether …