In situ forming and reactive oxygen species-scavenging gelatin hydrogels for enhancing wound healing efficacy

P Le Thi, Y Lee, DL Tran, TTH Thi, JI Kang, KM Park… - Acta biomaterialia, 2020 - Elsevier
The overexpression of reactive oxygen species (ROS) contributes to the pathogenesis of
numerous diseases such as atherosclerosis, myocardial infarction, cancer, and chronic …

In situ forming ROS-scavenging hybrid hydrogel loaded with polydopamine-modified fullerene nanocomposites for promoting skin wound healing

X Chen, Y Zhang, W Yu, W Zhang, H Tang… - Journal of …, 2023 - Springer
Background Excessive oxidative stress at the wound sites always leads to a prolonged
healing and even causes chronic inflammatory wounds. Therefore, antioxidative dressings …

Glycosaminoglycan-based hydrogel delivery system regulates the wound microenvironment to rescue chronic wound healing

X Zhang, J Feng, W Feng, B Xu, K Zhang… - … Applied Materials & …, 2022 - ACS Publications
Chronic wounds cannot proceed through the normal, orderly, and timely sequence of repair.
The adverse cycle between excess reactive oxide species (ROS) and a persistent …

[HTML][HTML] Green tea derivative-based hydrogel with ROS-scavenging property for accelerating diabetic wound healing

G Jia, Z Li, H Le, Z Jiang, Y Sun, H Liu, F Chang - Materials & Design, 2023 - Elsevier
The accumulation of reactive oxygen species (ROS) in the oxidative stress
microenvironment of diabetic wounds often results in delayed wound healing. In this study, a …

Enzyme-catalyzed in situ forming gelatin hydrogels as bioactive wound dressings: effects of fibroblast delivery on wound healing efficacy

Y Lee, JW Bae, JW Lee, W Suh, KD Park - Journal of Materials …, 2014 - pubs.rsc.org
In this study, in situ forming gelatin hydrogels via horseradish peroxidase (HRP)-catalyzed
cross-linking were developed to serve as bioactive wound dressings with suitable tissue …

Mild hyperthermia-assisted ROS scavenging hydrogels achieve diabetic wound healing

X Qi, X Tong, S You, R Mao, E Cai, W Pan… - ACS macro …, 2022 - ACS Publications
Excessive reactive oxygen species (ROS) production induces oxidative damage to
biomolecules, which can lead to the development of chronic diseases. Biocompatible …

Glucose‐Responsive Antioxidant Hydrogel Accelerates Diabetic Wound Healing

F Chen, J Qin, P Wu, W Gao… - Advanced Healthcare …, 2023 - Wiley Online Library
Diabetic complications can be ameliorated by inhibiting excessive oxidative stress with
antioxidants. To enhance therapeutic intervention, it is crucial to develop intelligent scaffolds …

Novel glucose-responsive antioxidant hybrid hydrogel for enhanced diabetic wound repair

Z Xu, G Liu, J Huang, J Wu - ACS applied materials & interfaces, 2022 - ACS Publications
Antioxidant hydrogel has exhibited great potential for diabetic wound treatment. However, it
is still a difficult challenge to realize reactive oxygen species (ROS) scavenging in an …

Cell infiltrative hydrogel fibrous scaffolds for accelerated wound healing

X Zhao, X Sun, L Yildirimer, Q Lang, ZYW Lin, R Zheng… - Acta biomaterialia, 2017 - Elsevier
Abstract Development of natural protein-based fibrous scaffolds with tunable physical
properties and biocompatibility is highly desirable to construct three-dimensional (3D), fully …

Cerium oxide nanoparticle-loaded gelatin methacryloyl hydrogel wound-healing patch with free radical scavenging activity

R Augustine, AA Zahid, A Hasan… - … Science & Engineering, 2020 - ACS Publications
Nonhealing wounds in diabetic patients are a critical challenge, which often cause
amputation and mortality. High levels of oxidative stress and aberrations in antioxidant …