Abstract Solid Lipid Nanoparticles (SLNs) composed of biodegradable physiological lipids
have been widely proposed as efficient drug delivery systems, also for ophthalmic …

The aim of this study was to develop cyclosporine A (CsA) loaded solid lipid nanoparticles
(SLN) associated with chitosan (CS), to improve interaction and internalization in corneal …

The present study aimed to develop and optimize chitosan coated solid lipid nanoparticles
(chitosan-SLNs) encapsulated with methazolamide. Chitosan-SLNs were successfully …

In the recent decades, various controlled delivery systems have been introduced with the
aim to improve solubility, stability and bioavailability of poorly absorbed drugs. Among all …

The unique properties and characteristics of ocular tissues and the whole set of defence
mechanisms of the ocular globe make the instillation of ocular drugs into a difficult task with …

Due to the multiple barriers imposed by the eye against the penetration of drugs, the ocular
delivery and targeting are considered difficult to achieve. A major challenge in ocular drug …

Drug delivery carriers can maintain effective therapeutic concentrations in the eye. To this
end, we developed lipid nanoparticles (L/NPs) in which the surface was modified with …

The objective of this study was to propose novel surface-modified nanostructured lipid
carriers with partially deacetylated water-soluble chitosan (NLC–PDSC) as an efficient …

The objective of the present investigation was to explore the potential of the Chitosan
Oligosaccharides (COS)-coated NLC (nanostructured lipid carrier) for ocular drug delivery …

This study is focused on further understanding the characteristics of chitosan-N-
acetylcysteine surface-modified nanostructured lipid carriers (CS-NAC-NLCs) in their …