H Zhao, Y Chen, P Shen, L Gong - Frontiers in Cell and …, 2021 - frontiersin.org
Uveal melanoma (UVM) is the most common primary intraocular cancer in adults. Increasing evidence has demonstrated that immune cell infiltration (ICI) is crucial in predicting patient …
X Lv, M Ding, Y Liu - Frontiers in Immunology, 2022 - frontiersin.org
Background Numerous studies indicated that tumor-infiltrated immune cells (TIC) in the microenvironment are substantially linked to immunotherapy response and cancer …
Y Sun, J Wu, Y Yuan, Y Lu, M Luo, L Lin… - Frontiers in cell and …, 2021 - frontiersin.org
Background CD8+ T cells work as a key effector of adaptive immunity and are closely associated with immune response for killing tumor cells. It is crucial to understand the role of …
S Chen, Z Tang, Q Wan, W Huang, X Li, X Huang… - Cancer Cell …, 2024 - Springer
Purpose Uveal melanoma (UM) is adults' most common primary intraocular malignant tumor. It has been observed that 40% of patients experience distant metastasis during subsequent …
C Zhang, J Xiao, L Fa, F Jiang, H Jiang, L Zhou… - BMC …, 2023 - Springer
Current immunotherapies are unsatisfactory against uveal melanoma (UM); however, elevated CD8+ T cell infiltration level indicates poor prognosis in UM. Here, we aimed to …
S García-Mulero, MH Alonso, LP Del Carpio… - International journal of …, 2021 - mdpi.com
Uveal melanoma (UM) is a malignant tumor that arises in the melanocytes of the uveal tract. It is the most frequent eye cancer, and despite new therapeutic approaches, prognosis is still …
X Sun, Q Li, G Xu - International Ophthalmology, 2023 - Springer
Purpose The current study aimed to reveal a novel immune-related signature to evaluate immune infiltration status and the survival outcome for patients with uveal melanoma (UM) …
Z Zhang, J Su, L Li, W Du - Frontiers in Cell and Developmental …, 2021 - frontiersin.org
The tumor microenvironment is an important factor for the immunotherapy of tumor patients. The sequenced transcriptome data can be used to describe the tumor microenvironment …
J Wang, M Liu, J Sun, Z Zhang - Journal of Cancer Research and Clinical …, 2024 - Springer
Background Uveal melanoma (UM) is an aggressive intraocular malignant tumor. The present study aimed to identify the key genes associated with UM metastasis and …