Major depressive disorder (MDD) is a complex psychiatric condition with strong genetic
predisposition. The association of MDD with genetic polymorphisms, such as Val66Met …

Etiological research has indicated the gene–environment interaction (G× E) on adolescent
anxiety. This study aimed to examine how the BDNF Val66Met polymorphism interacted with …

Genetic factors were shown to play a major role in both variation of treatment response and
incidence of adverse effects to medication in affective disorders. Nevertheless, there is still a …

Background Although several lines of evidences suggest that the brain-derived neurotrophic
factor (BDNF) Val66Met polymorphism may be involved in the pathophysiology of …

Background We test the hypothesis that the functional Val66Met polymorphism of BDNF
interacts with recent life events to produce onset of new depressive episodes. We also …

BACKGROUND: Gene× environment (G× E) interactions are known to predict susceptibility
to disorders such as depression and anxiety. Adverse experiences in childhood and number …

Background Major depressive disorder (MDD) and obesity are global health problems that
frequently co-occur. Among shared etiological factors, genetic variation at the brain-derived …

Major depressive disorder (MDD) is a genetically complex and heterogeneous disorder.
Accumulating evidence suggests that brain derived neurotrophic factor (BDNF) is involved in …

Objective Coping with cancer is an important determinant of psychological morbidity, quality
of life, and treatment adherence in cancer patients. The aim of this study was to elucidate the …

Objectives. Lower levels of serum brain derived neurotrophic factor (BDNF) is one of the
best known biomarkers of depression. To identify genetic variants associated with serum …