Aims To assess the implications of low testosterone on cardiovascular risk factors, metabolic
syndrome (MES) and clinical outcomes in Chinese men with Type 2 Diabetes (T2D) …

Generally, high testosterone levels within the physiological range are associated with a
more favourable cardiometabolic profile. Although the FDA has approved testosterone for …

Background Low-density lipoprotein (LDL)-cholesterol is positively associated with
cardiovascular disease (CVD) and inversely associated with type 2 diabetes, which could …

Sex hormone-binding globulin (SHBG) is a glycoprotein responsible for the transport and
biologic availability of sex steroid hormones, primarily testosterone and estradiol. SHBG has …

Testosterone is a key hormone in the pathology of metabolic diseases such as obesity. Low
testosterone levels are associated with increased fat mass (particularly central adiposity) …

Low testosterone levels in men have been linked to decreased physical and mental function,
as well as a reduced quality of life. Previous prospective observational studies have …

Normal levels of male sex hormones are essential to men's health. Many studies
demonstrate that hypogonadal men are at higher risk for developing a host of metabolic …

Due to the fundamental biological differences between males and females, nearly all
aspects of metabolism, including energy balance as well as glucose and lipid metabolism …

Testosterone plays a critical role in mediating fitness-related traits in many species. Although
it is highly responsive to environmental and social conditions, evidence from several species …

Lower testosterone levels in men are observationally associated with worse health, but it is
unclear whether they contribute to well-established social gradients in health. Mendelian …