The number of approved drugs for the market is decreasing in recent years and calls for
more effective methods to discover a higher number of successful compound candidates …

Medicinal chemistry, at the nexus of chemistry, biology, and pharmacology, continually
evolves to address the dynamic landscape of human health challenges. This abstract …

Computational drug design and discovery have taken center stage attention during the time
of COVID-19. The science community acknowledges the importance of ligand-based drug …

Drug research requires interdisciplinary team-work at the interface between chemistry,
biology and medicine. Therefore, the new topic-related series should cover all relevant …

Chemical biology is the scientific discipline that deals with the application of chemical
techniques and often small molecules produced through synthetic chemistry, to the …

Historically, natural products chemistry and synthetic organic chemistry have been the
driving force for drug discovery. Natural products chemistry has provided impressive …

To date, computational approaches have been recognized as a key component in drug
design and discovery workflows. Developed to help researchers save time and reduce …

Despite breakthroughs in medical sciences, drug development remains a timeconsuming,
expensive, challenging, and inefficient process with a high failure rate for novel therapeutic …

In the past decade or so there has been a dramatic increase in the number of computational
applications and tools that have been developed to enable medicinal chemists to prosecute …

Modern drug design and discovery is an increasingly complex process, where a wide range
of actors with many different backgrounds work together toward the unifying goal of …