Melanins, pigments of photoprotection and camouflage, are very photoreactive and can both
absorb and emit active oxygen species. Nevertheless, black skinned individuals rarely …

Highly pigmented, dark skin is more resistant to the harmful effects of solar ultraviolet
radiation than light-colored human skin. The extent to which tanning protects skin from …

Epidermal melanin pigment is believed to prevent development of ultraviolet (UV)–induced
skin cancer by shielding cell nuclei and reducing DNA damage formation. It has not been …

Cutaneous malignant melanoma (CMM) is one of the most rapidly increasing cancers in the
western world (Bowden, 2004). Frequency of its occurrence is closely associated with skin …

Melanin is both photosensitizer and photoprotector. Skin cancer rates decrease with
increasing constitutive pigmentation, yet the pigment has been shown to be photoreactive …

The goal of this investigation was to correlate the melanin content in human pigmentary cells
with the generation of UVB‐induced photoproducts and to examine the relationship between …

It was the aim of these studies to determine whether the presence of intracellular melanin
quantitatively alters the rate of production of thymine dimers in DNA of irradiated cells in …

Melanin protects the skin against DNA damage induced by direct absorption of sunlight's UV
radiation. Yet, irradiating melanin in vitro or in cultured cells also generates active oxygen …

The question of whether melanins are photoprotecting and/or photosensitizing in human
skin cells continues to be debated. To evaluate the role of melanin upon UVA irradiation …

Melanin is thought to serve in photoprotection. To investigate this, we have compared the
responses of cultured human melanocytes derived from different pigmentary phenotypes …