Potential therapeutic natural compounds for the treatment of Alzheimer's disease

Q Huang, W Wu, Y Wen, S Lu, C Zhao - Phytomedicine, 2024 - Elsevier
Background Alzheimer's disease (AD) is a complicated neurodegenerative disease with
cognitive impairment occurring in the older people, in which extracellular accumulation of β …

Cholesterol dysmetabolism in Alzheimer's disease: a starring role for astrocytes?

E Staurenghi, S Giannelli, G Testa, B Sottero… - Antioxidants, 2021 - mdpi.com
In recent decades, the impairment of cholesterol metabolism in the pathogenesis of
Alzheimer's disease (AD) has been intensively investigated, and it has been recognized to …

Linking lipids to Alzheimer's disease: cholesterol and beyond

G Di Paolo, TW Kim - Nature Reviews Neuroscience, 2011 - nature.com
Lipid-mediated signalling regulates a plethora of physiological processes, including crucial
aspects of brain function. In addition, dysregulation of lipid pathways has been implicated in …

Current therapies and new strategies for the management of Alzheimer's disease

OG Aderinwale, HW Ernst… - American Journal of …, 2010 - journals.sagepub.com
Alzheimer's disease (AD) is a devastating neurodegenerative disorder that currently affects
millions of Americans. There is no cure at present and no real long-term hope for patients …

[HTML][HTML] Alterations in cholesterol metabolism as a risk factor for developing Alzheimer's disease: Potential novel targets for treatment

R Loera-Valencia, J Goikolea… - The Journal of steroid …, 2019 - Elsevier
Alzheimer's disease (AD) is the most common form of dementia and it is characterized by the
deposition of amyloid-β (Aβ) plaques and neurofibrillary tangles in the brain. However, the …

[图书][B] Phytomedicine and Alzheimer's disease

A Bhattacharjee, A Ramakrishna, M Obulesu - 2020 - books.google.com
Alzheimer's disease, one of the most rapidly growing neurodegenerative disorders, is
characterized by a progressive loss of memory. Despite several advances in the field of …

Brain cholesterol pathology is the cause of Alzheimer's disease

AR Koudinov, NV Koudinova - Clin. Med. Health Res, 2001 - staticweb.bmj.com
Several recent reports provided important knowledge on how “inhibiting cholesterol
production in the brain might inhibit amyloid b (Ab) ABBR production, and reduce the …

The multifaceted role of neuroprotective plants in Alzheimer's Disease treatment

T Zieneldien, J Kim, C Cao - Geriatrics, 2022 - mdpi.com
Alzheimer's disease (AD) is an age-related, progressive neurodegenerative disorder
characterized by impaired cognition, memory loss, and altered personality. Many of the …

Neuroprotective herbs for the management of Alzheimer's disease

J Gregory, YV Vengalasetti, DE Bredesen, RV Rao - Biomolecules, 2021 - mdpi.com
Background—Alzheimer's disease (AD) is a multifactorial, progressive, neurodegenerative
disease that is characterized by memory loss, personality changes, and a decline in …

[HTML][HTML] Leveraging hallmark Alzheimer's molecular targets using phytoconstituents: current perspective and emerging trends

PA Dhage, AA Sharbidre, SP Dakua… - Biomedicine & …, 2021 - Elsevier
Abstract Alzheimer's disease (AD), a type of dementia, severely distresses different brain
regions. Characterized by various neuropathologies, it interferes with cognitive functions …