A myocardin-related transcription factor regulates activity of serum response factor in Drosophila

Z Han, X Li, J Wu, EN Olson - Proceedings of the National …, 2004 - National Acad Sciences
Serum response factor (SRF) regulates genes involved in cell proliferation, migration,
cytoskeletal organization, and myogenesis. Myocardin and myocardin-related transcription …

[HTML][HTML] Early postnatal cardiac changes and premature death in transgenic mice overexpressing a mutant form of serum response factor

X Zhang, J Chai, G Azhar, P Sheridan… - Journal of Biological …, 2001 - ASBMB
Serum response factor (SRF) is a key regulator of a number of extracellular signal-regulated
genes important for cell growth and differentiation. A form of the SRF gene with a double …

The myocardin-related transcription factor, MASTR, cooperates with MyoD to activate skeletal muscle gene expression

SM Meadows, AS Warkman… - Proceedings of the …, 2008 - National Acad Sciences
The myocardin family proteins (myocardin, MRTF-A, and MRTF-B) are serum response
factor (SRF) cofactors and potent transcription activators. Gene-ablation studies have …

The Drosophila SRF homolog is expressed in a subset of tracheal cells and maps within a genomic region required for tracheal development

M Affolter, J Montagne, U Walldorf, J Groppe… - …, 1994 - journals.biologists.com
The Drosophila homolog of the vertebrate serum response factor (SRF) was isolated by low
stringency hybridization. Nucleotide sequence analysis revealed that the Drosophila SRF …

Restricted inactivation of serum response factor to the cardiovascular system

JM Miano, N Ramanan, MA Georger… - Proceedings of the …, 2004 - National Acad Sciences
Serum response factor (SRF) directs programs of gene expression linked to growth and
muscle differentiation. To investigate the role of SRF in cardiovascular development, we …

Requirement for serum response factor for skeletal muscle growth and maturation revealed by tissue-specific gene deletion in mice

S Li, MP Czubryt, J McAnally… - Proceedings of the …, 2005 - National Acad Sciences
Serum response factor (SRF) controls the transcription of muscle genes by recruiting a
variety of partner proteins, including members of the myocardin family of transcriptional …

[HTML][HTML] Myocardin-related transcription factors are required for cardiac development and function

MH Mokalled, KJ Carroll, BK Cenik, B Chen, N Liu… - Developmental …, 2015 - Elsevier
Abstract Myocardin-Related Transcription Factors A and B (MRTF-A and MRTF-B) are highly
homologous proteins that function as powerful coactivators of serum response factor (SRF) …

The pruned gene encodes the Drosophila serum response factor and regulates cytoplasmic outgrowth during terminal branching of the tracheal system

K Guillemin, J Groppe, K Dücker, R Treisman… - …, 1996 - journals.biologists.com
We identified a Drosophila gene, pruned, that regulates formation of the terminal branches
of the tracheal (respiratory) system. These branches arise by extension of long cytoplasmic …

[HTML][HTML] Activation of cardiac gene expression by myocardin, a transcriptional cofactor for serum response factor

DZ Wang, PS Chang, Z Wang, L Sutherland… - Cell, 2001 - cell.com
Serum response factor (SRF) regulates transcription of numerous muscle and growth factor-
inducible genes. Because SRF is not muscle specific, it has been postulated to activate …

[HTML][HTML] Organization and myogenic restricted expression of the murine serum response factor gene: a role for autoregulation

NS Belaguli, LA Schildmeyer, RJ Schwartz - Journal of Biological Chemistry, 1997 - ASBMB
Serum response factor (SRF), a member of an ancient family of DNA-binding proteins, is
generally assumed to be a ubiquitous transcription factor involved in regulating growth factor …