SARS-CoV-2: immunity, challenges with current vaccines, and a novel perspective on mucosal vaccines
The global rollout of COVID-19 vaccines has played a critical role in reducing pandemic
spread, disease severity, hospitalizations, and deaths. However, the first-generation …
spread, disease severity, hospitalizations, and deaths. However, the first-generation …
Mucosal vaccines for SARS-CoV-2: scientific gaps and opportunities—workshop report
JM Knisely, LE Buyon, R Mandt, R Farkas… - npj Vaccines, 2023 - nature.com
On November 7th and 8th, 2022, The National Institute of Allergy and Infectious Diseases
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …
(NIAID), part of the National Institutes of Health (NIH), The Coalition for Epidemic …
[HTML][HTML] Promises and challenges of mucosal COVID-19 vaccines
APS Rathore, ALS John - Vaccine, 2023 - Elsevier
Abstract Coronavirus disease-2019 (COVID-19) is an ongoing pandemic caused by the
newly emerged virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
newly emerged virus severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) …
Prospects for mucosal vaccine: shutting the door on SARS-CoV-2
The sudden emergence of a highly transmissible and pathogenic coronavirus SARS-CoV-2
in December 2019 from China and its rapid global spread has posed an international health …
in December 2019 from China and its rapid global spread has posed an international health …
[HTML][HTML] Mucosal COVID-19 vaccines: Risks, benefits and control of the pandemic
D Miteva, M Peshevska-Sekulovska… - World Journal of …, 2022 - ncbi.nlm.nih.gov
Based on mucosal immunization to promote both mucosal and systemic immune responses,
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …
next-generation coronavirus disease 2019 (COVID-19) vaccines would be administered …
[HTML][HTML] Dealing with a mucosal viral pandemic: lessons from COVID-19 vaccines
V Mouro, A Fischer - Mucosal immunology, 2022 - Elsevier
The development and deployment of vaccines against COVID-19 demonstrated major
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
successes in providing immunity and preventing severe disease and death. Yet SARS-CoV …
Mucosal vaccines for SARS-CoV-2: triumph of hope over experience
D Pilapitiya, AK Wheatley, HX Tan - EBioMedicine, 2023 - thelancet.com
Currently approved COVID-19 vaccines administered parenterally induce robust systemic
humoral and cellular responses. While highly effective against severe disease, there is …
humoral and cellular responses. While highly effective against severe disease, there is …
Development of SARS-CoV-2 vaccines: should we focus on mucosal immunity?
L Moreno-Fierros, I García-Silva… - Expert Opinion on …, 2020 - Taylor & Francis
The COVID-19 pandemic caused by the SARS-CoV-2 virus is having an unprecedented
impact on global health derived from its quick spread, which is attributed to its high stability …
impact on global health derived from its quick spread, which is attributed to its high stability …
Challenges and prospects in developing future SARS-CoV-2 vaccines: Overcoming original antigenic sin and inducing broadly neutralizing antibodies
JP Evans, SL Liu - The Journal of Immunology, 2023 - journals.aai.org
The impacts of the COVID-19 pandemic led to the development of several effective SARS-
CoV-2 vaccines. However, waning vaccine efficacy as well as the antigenic drift of SARS …
CoV-2 vaccines. However, waning vaccine efficacy as well as the antigenic drift of SARS …
Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
The emerging SARS-CoV-2 variants of concern (VOCs) threaten the effectiveness of current
COVID-19 vaccines administered intramuscularly and designed to only target the spike …
COVID-19 vaccines administered intramuscularly and designed to only target the spike …