Three-dimensional co-cultures of human endothelial cells and embryonic stem cell-derived pericytes inside a microfluidic device
Organs-on-chips are microengineered in vitro tissue structures that can be used as platforms
for physiological and pathological research. They provide tissue-like microenvironments in …
for physiological and pathological research. They provide tissue-like microenvironments in …
Low-cost rapid prototyping and assembly of an open microfluidic device for a 3D vascularized organ-on-a-chip
Q Li, K Niu, D Wang, L Xuan, X Wang - Lab on a Chip, 2022 - pubs.rsc.org
Reconstruction of 3D vascularized microtissues within microfabricated devices has rapidly
developed in biomedical engineering, which can better mimic the tissue microphysiological …
developed in biomedical engineering, which can better mimic the tissue microphysiological …
Emulating human microcapillaries in a multi-organ-chip platform
T Hasenberg, S Mühleder, A Dotzler, S Bauer… - Journal of …, 2015 - Elsevier
Current microfluidic chip-based tissue culture systems lack a capillary endothelial vessel
system, which would enable perfusion with blood. We utilise spatial cell cultures to populate …
system, which would enable perfusion with blood. We utilise spatial cell cultures to populate …
Vascularized microfluidic organ-chips for drug screening, disease models and tissue engineering
Highlights•Several viable methods currently exist to create vascularized in vitro
tissues.•Progress has been made in developing systems that mimic specific organs or …
tissues.•Progress has been made in developing systems that mimic specific organs or …
A new microfluidic model that allows monitoring of complex vascular structures and cell interactions in a 3D biological matrix
CGM van Dijk, MM Brandt, N Poulis, J Anten… - Lab on a Chip, 2020 - pubs.rsc.org
Microfluidic organ-on-a-chip designs are used to mimic human tissues, including the
vasculature. Here we present a novel microfluidic device that allows the interaction of …
vasculature. Here we present a novel microfluidic device that allows the interaction of …
[HTML][HTML] Engineered vasculature for organ-on-a-chip systems
Organ-on-a-chip technology, a promising three-dimensional (3D) dynamic culture method,
ensures accurate and efficient cell culture and has great potential for replacing animal …
ensures accurate and efficient cell culture and has great potential for replacing animal …
Tailoring biomaterials for biomimetic organs-on-chips
Organs-on-chips are microengineered microfluidic living cell culture devices with
continuously perfused chambers penetrating to cells. By mimicking the biological features of …
continuously perfused chambers penetrating to cells. By mimicking the biological features of …
Engineering organ-on-a-chip to accelerate translational research
We guide the use of organ-on-chip technology in tissue engineering applications. Organ-on-
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
chip technology is a form of microengineered cell culture platform that elaborates the in-vivo …
Perfusable micro-vascularized 3D tissue array for high-throughput vascular phenotypic screening
Microfluidic organ-on-a-chip technologies have enabled construction of biomimetic
physiologically and pathologically relevant models. This paper describes an injection …
physiologically and pathologically relevant models. This paper describes an injection …
Human lung small airway-on-a-chip protocol
Organs-on-chips are microfluidic cell culture devices created using microchip manufacturing
techniques that contain hollow microchannels lined by living cells, which recreate …
techniques that contain hollow microchannels lined by living cells, which recreate …