Emerging translational research in neurological and psychiatric diseases: from in vitro to in vivo models

M Tanaka, Á Szabó, L Vécsei… - International journal of …, 2023 - mdpi.com
Revealing the underlying pathomechanisms of neurological and psychiatric disorders,
searching for new biomarkers, and developing novel therapeutics all require translational …

From lab to life: Exploring cutting-edge models for neurological and psychiatric disorders

M Tanaka, L Vécsei - Biomedicines, 2024 - mdpi.com
Neuroscience, neurology, and psychiatry are rapidly evolving fields that aim to understand
the complex mechanisms underlying brain function and dysfunction, as well as to develop …

Shared mechanisms across the major psychiatric and neurodegenerative diseases

TS Wingo, Y Liu, ES Gerasimov, SM Vattathil… - Nature …, 2022 - nature.com
Several common psychiatric and neurodegenerative diseases share epidemiologic risk;
however, whether they share pathophysiology is unclear and is the focus of our …

The molecular medicine revolution and psychiatry: bridging the gap between basic neuroscience research and clinical psychiatry

TD Gould, HK Manji - Journal of Clinical Psychiatry, 2004 - psychiatrist.com
Recent years have witnessed a considerable increase in both fundamental knowledge and
available experimental techniques in the basic neurosciences. Unfortunately, clinical …

Neurodegeneration in cognitive impairment and mood disorders for experimental, clinical and translational neuropsychiatry

S Battaglia, A Avenanti, L Vécsei, M Tanaka - Biomedicines, 2024 - mdpi.com
Neurodegeneration poses a significant challenge for the fields of neuroscience and
medicine, as it is the underlying cause of the development and advancement of numerous …

[图书][B] Neurobiology of brain disorders: biological basis of neurological and psychiatric disorders

MJ Zigmond, CA Wiley, MF Chesselet - 2022 - books.google.com
Neurobiology of Brain Disorders: Biological Basis of Neurological and Psychiatric Disorders,
Second Edition provides basic scientists a comprehensive overview of neurological and …

[HTML][HTML] Psychiatric disorders: diagnosis to therapy

JH Krystal - Cell, 2014 - cell.com
Recent findings in a range of scientific disciplines are challenging the conventional wisdom
regarding the etiology, classification, and treatment of psychiatric disorders. This Review …

[HTML][HTML] Putting the “biology” back into “neurobiology”: the strength of diversity in animal model systems for neuroscience research

J Keifer, CH Summers - Frontiers in Systems Neuroscience, 2016 - frontiersin.org
Current trends in neuroscience research have moved toward a reliance on rodent animal
models to study most aspects of brain function. Such laboratory-reared animals are highly …

Between destiny and disease: genetics and molecular pathways of human central nervous system aging

C Glorioso, E Sibille - Progress in neurobiology, 2011 - Elsevier
Aging of the human brain is associated with “normal” functional, structural, and molecular
changes that underlie alterations in cognition, memory, mood and motor function, amongst …

[HTML][HTML] Innovative solutions to novel drug development in mental health

TR Insel, V Voon, JS Nye, VJ Brown… - Neuroscience & …, 2013 - Elsevier
There are many new advances in neuroscience and mental health which should lead to a
greater understanding of the neurobiological dysfunction in neuropsychiatric disorders and …