Genome-wide association studies (GWAS) of psychiatric disorders have identified multiple
genetic associations with such disorders, but better methods are needed to derive the …

Schizophrenia is a severe, complex mental disorder characterized by a combination of
positive symptoms, negative symptoms, and impaired cognitive function. Schizophrenia is …

Objective: We performed a whole-genome expression study to clarify the nature of the
biological processes mediating between inherited genetic variations and cognitive …

Genome-wide association studies (GWASs) have identified over 180 independent
schizophrenia risk loci. Nevertheless, how the risk variants in the reported loci confer …

Breakthroughs in genomics have begun to unravel the genetic architecture of schizophrenia
risk, providing methods for quantifying schizophrenia polygenic risk based on common …

Cognitive impairments constitute a core feature of schizophrenia, and a genetic overlap
between schizophrenia and cognitive functioning in healthy individuals has been identified …

Causal genes and variants within genome-wide association study (GWAS) loci can be
identified by integrating GWAS statistics with expression quantitative trait loci (eQTL) and …

The new GWAS from the Schizophrenia Working Group of the Psychiatric Genomics
Consortium (2014) clearly validates a genetic approach to understanding schizophrenia …

Susceptibility to schizophrenia and bipolar disorder may involve a substantial, shared
contribution from thousands of common genetic variants, each of small effect. Identifying …

Background While a variety of evidence supports a prenatal component in schizophrenia,
there are few data regarding the cell populations involved. We sought to identify cells of the …