Schizophrenia is a common, complex, heterogeneous psychiatric syndrome which can have
profound impacts on affected individuals and imposes significant burdens on society …

Common genetic variants identified in genome-wide association studies (GWAS) show
varying degrees of genetic pleiotropy across complex human disorders. Clinical studies of …

Schizophrenia is a severe mental disorder with a large genetic component. Recent genome-
wide association studies (GWAS) have identified many schizophrenia-associated common …

Schizophrenia is a highly polygenic brain disorder. The main hypothesis for disease etiology
in schizophrenia primarily focuses on the role of dysfunctional synaptic transmission …

Over 100 loci are now associated with schizophrenia risk as identified by single nucleotide
polymorphisms (SNPs) in genome-wide association studies. These findings mean that …

Schizophrenia and the affective disorders, here comprising bipolar disorder and major
depressive disorder, are psychiatric illnesses that lead to significant morbidity and mortality …

We have used a translational convergent functional genomics (CFG) approach to identify
and prioritize genes involved in schizophrenia, by gene-level integration of genome-wide …

Background Parkinson's disease (PD) and schizophrenia (SCZ) are heritable brain
disorders that involve dysregulation of the dopaminergic system. Epidemiological studies …

There has been intense debate over the immunological basis of schizophrenia, and the
potential utility of adjunct immunotherapies. The major histocompatibility complex is …

Schizophrenia genome-wide association studies have identified> 150 regions of the
genome associated with disease risk, yet there is little evidence that coding mutations …