In spite of the importance of plasmids in bacterial adaptation, we have a poor understanding
of their dynamics. It is not known if or how plasmids persist in and spread through (invade) a …

IncP-1 plasmids are known to be promiscuous, but it is not understood if they are equally
well adapted to various species within their host range. Moreover, little is known about their …

It is difficult to understand plasmid maintenance in the absence of selection and theoretical
models predict the conditions for plasmid persistence to be limited. Plasmid-associated …

Plasmids are important drivers of bacterial evolution, but it is challenging to understand how
plasmids persist over the long term because plasmid carriage is costly. Classical models …

Plasmids have a key role in the horizontal transfer of genes among bacteria. Although
plasmids are catalysts for bacterial evolution, it is challenging to understand how they can …

Bacterial plasmids are extra-chromosomal genetic elements that code for a wide variety of
phenotypes in their bacterial hosts and are maintained in bacterial communities through …

The ability of bacterial plasmids to adapt to novel hosts and thereby shift their host range is
key to their long-term persistence in bacterial communities. Promiscuous plasmids of the …

Background Understanding the survival of resistance plasmids in the absence of selective
pressure for the antibiotic resistance genes they carry is important for assessing the value of …

Plasmid persistence in bacterial populations is strongly influenced by the fitness effects
associated with plasmid carriage. However, plasmid fitness effects in wild-type bacterial …

Plasmid pB15 was previously shown to evolve increased horizontal (infectious) transfer at
the expense of reduced vertical (intergenerational) transfer and vice versa, a key trade-off …