S Batool, K Vuthaluru, A Hassan, O Bseiso, Z Tehseen… - Cureus, 2023 - ncbi.nlm.nih.gov
This meta-analysis was conducted with the aim to assess the safety and efficacy of favipiravir in treating patients with coronavirus disease 2019 (COVID-19). It was carried out …
At a crucial time with rapid spread of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant globally, the United States Food and Drug Administration …
WP Painter, W Holman, JA Bush… - Antimicrobial agents …, 2021 - Am Soc Microbiol
ABSTRACT Molnupiravir (EIDD-2801/MK-4482), the prodrug of the active antiviral ribonucleoside analog β-d-N4-hydroxycytidine (NHC; EIDD-1931), has activity against a …
D Paraskevis, M Gkova, K Mellou… - The Journal of …, 2023 - academic.oup.com
Background Using a retrospective cohort study design, we aimed to evaluate the effectiveness of molnupiravir and nirmatrelvir/ritonavir in patients with SARS-CoV-2 who …
There is an urgent need for an effective, oral, direct-acting therapeutic to block transmission of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and prevent progression …
Interim phase III trial results, released through a press release by the drug's manufacturer, MSD, found that molnupiravir reduced the risk of admission to hospital or death by around …
LA Petty, PN Malani - JAMA, 2022 - jamanetwork.com
Twonewantiviralmedications, ritonavir-boostednirmatrelvir (Paxlovid, ie, nirmatrelvir- ritonavir) and molnupiravir (Lagevrio), are currently availableintheUSunderemergencyuseautho …
BM Maas, J Strizki, RR Miller, S Kumar… - Clinical and …, 2024 - Wiley Online Library
Molnupiravir is an oral prodrug of the broadly active, antiviral ribonucleoside analog N‐ hydroxycytidine (NHC). The primary circulating metabolite NHC is taken up into cells and …
Molnupiravir (Lagevrio®) is an orally-administered antiviral prodrug that inhibits replication of RNA viruses through viral error induction. It is being developed by Merck and Ridgeback …