Sustained life stress and low socioeconomic status are among the major causes of aging-
related diseases and decreased life expectancy. Experimental rodent models can help to …

Stress and low socioeconomic status in humans confer increased vulnerability to morbidity
and mortality. However, this association is not mechanistically understood nor has its …

Several social dimensions including social integration, status, early-life adversity, and their
interactions across the life course can predict health, reproduction, and mortality in humans …

It is known that stress alters homeostasis and may lead to accelerated aging. However, little
is known about the contribution of innate susceptibility to stress to the deterioration of …

Social adversity can increase the age-associated risk of disease and death, yet the
biological mechanisms that link social adversities to aging remain poorly understood. Long …

BACKGROUND The social environment shapes human health, producing strong
relationships between social factors, disease risk, and survival. The strength of these links …

Socioemotional health is positively correlated with improved cognitive and physical aging.
Despite known sex differences in socioemotional behaviors and the trajectory of aging, the …

Chronic social stress is a predictor of both aging‐related disease and mortality risk. Hence,
chronic stress has been hypothesized to directly exacerbate the process of physiological …

Over the last decades the burden of disease in Western countries has shifted from
comparably easily treated infectious diseases to more complex diseases, such as the …

Chronic stress is a risk factor for numerous aging-related diseases and has been shown to
shorten lifespan in humans and other social mammals. Yet how life stress causes such a …