Early diagnosis of Alzheimer's disease: contribution of structural neuroimaging

G Aël Chetelat, JC Baron - Neuroimage, 2003 - Elsevier
To accurately predict the development of Alzheimer's disease (AD) at its predementia stage
would be a major breakthrough from both therapeutic and research standpoints. In this …

Neuroimaging of hippocampal atrophy in early recognition of Alzheimer´ s disease–a critical appraisal after two decades of research

J Schröder, J Pantel - Psychiatry Research: Neuroimaging, 2016 - Elsevier
As a characteristic feature of Alzheimer´ s disease (AD) hippocampal atrophy (HA) can be
demonstrated in the majority of patients by using neuroimaging techniques in particular …

Hippocampus and entorhinal cortex in mild cognitive impairment and early AD

C Pennanen, M Kivipelto, S Tuomainen… - Neurobiology of …, 2004 - Elsevier
Magnetic resonance imaging (MRI) has been suggested as a useful tool in early diagnosis
of Alzheimer's disease (AD). Based on MRI-derived volumes, we studied the hippocampus …

[HTML][HTML] Predicting conversion from mild cognitive impairment to Alzheimer's disease using brain 1H-MRS and volumetric changes: a two-year retrospective follow-up …

M Mitolo, M Stanzani-Maserati, S Capellari, C Testa… - NeuroImage: Clinical, 2019 - Elsevier
This study investigated the ability of magnetic resonance spectroscopy (1 H-MRS) of
posterior cingulate cortex (PCC) and brain volumetry to predict the progression from mild …

Structural imaging biomarkers of Alzheimer's disease: predicting disease progression

SF Eskildsen, P Coupé, VS Fonov, JC Pruessner… - Neurobiology of …, 2015 - Elsevier
Optimized magnetic resonance imaging (MRI)–based biomarkers of Alzheimer's disease
(AD) may allow earlier detection and refined prediction of the disease. In addition, they could …

Alzheimer Disease: Quantitative Structural Neuroimaging for Detection and Prediction of Clinical and Structural Changes in Mild Cognitive Impairment1

LK McEvoy, C Fennema-Notestine, JC Roddey… - Radiology, 2009 - pubs.rsna.org
Purpose: To use structural magnetic resonance (MR) images to identify a pattern of regional
atrophy characteristic of mild Alzheimer disease (AD) and to investigate whether presence of …

Contribution of structural neuroimaging to the early diagnosis of Alzheimer's disease

MJ de Leon, A Convit, S DeSanti… - International …, 1997 - cambridge.org
There is compelling evidence for the early involvement of the hippocampal formation in the
natural history of Alzheimer's disease (AD). The evidence comes from recent …

The Alzheimer's Disease Neuroimaging Initiative: a review of papers published since its inception

MW Weiner, DP Veitch, PS Aisen, LA Beckett… - Alzheimer's & …, 2013 - Elsevier
Abstract The Alzheimer's Disease Neuroimaging Initiative (ADNI) is an ongoing,
longitudinal, multicenter study designed to develop clinical, imaging, genetic, and …

Imaging the evolution and pathophysiology of Alzheimer disease

W Jagust - Nature Reviews Neuroscience, 2018 - nature.com
Technologies for imaging the pathophysiology of Alzheimer disease (AD) now permit
studies of the relationships between the two major proteins deposited in this disease …

A meta-analysis of structural and functional brain imaging in dementia of the Alzheimer's type: a neuroimaging profile

KK Zakzanis, SJ Graham, Z Campbell - Neuropsychology review, 2003 - Springer
We conducted a quantitative review of the imaging literature using meta-analytic
methodology to characterize further the magnitude of hippocampal deficit in probable …