Muscle wasting resulting wholly or in part from disuse represents a serious medical
complication that, when prolonged, can increase morbidity and mortality. Although much …

The ever increasing burden of an aging population and pandemic of metabolic syndrome
worldwide demands further understanding of the modifiable risk factors in reducing disability …

Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

Maintenance of skeletal muscle mass and function is an incredibly nuanced balance of
anabolism and catabolism that can become distorted within different pathological conditions …

Loss of skeletal muscle mass occurs frequently in clinical settings in response to joint
immobilization and bed rest, and is induced by a combination of unloading and inactivity …

Disuse atrophy is the loss of skeletal muscle mass due to inactivity or lower than 'normal'use.
It is not only a furtive component of the 'modern'sedentary lifestyle but also a part of …

Skeletal muscle fibers have a unique capacity to adjust their metabolism and phenotype in
response to alternations in mechanical loading. Indeed, chronic mechanical loading leads to …

Muscle atrophy results from a variety of conditions such as disease states, neuromuscular
injuries, disuse, and aging. Absence of gravitational loading during spaceflight or long-term …

Background We determined the short‐term (ie 4 days) impacts of disuse atrophy in relation
to muscle protein turnover [acute fasted‐fed muscle protein synthesis (MPS)/muscle protein …

Situations such as the recovery from injury and illness can lead to enforced periods of
muscle disuse or unloading. Such circumstances lead to rapid skeletal muscle atrophy, loss …