Lipid rafts are dynamic assemblies of proteins and lipids that harbour many receptors and
regulatory molecules and so act as a platform for signal transduction. They float freely within …

Lipid rafts is a blanket term used to describe distinct areas in the plasma membrane rich in
certain lipids and proteins and which are thought to perform diverse functions. A large …

Experimental evidence indicates that the mammalian cell membrane is compartmentalized.
A structural feature that supports membrane segmentation implicates assemblies of selected …

During the past decade, the lipid‐raft hypothesis has focused attention on the role of
membrane domains in controlling cellular functions. Among the best‐studied roles of lipid …

The cells of both the adaptive and innate immune systems express a dizzying array of
receptors that transduce and integrate an enormous amount of information about the …

In response to appropriate stimulation, T lymphocytes from systemic lupus erythematosus
(SLE) patients exhibit increased and faster intracellular tyrosine phosphorylation and free …

Lipid rafts and caveolae play a pivotal role in organization of signaling by TLR4 and several
other immune receptors. Beyond the simple cataloguing of signaling events …

Evidence has accumulated over the past few years to suggest that specialized plasma
membrane regions enriched in cholesterol and glycolipids, called 'lipid rafts', are primarily …

Lipid rafts regulate the initiation of cellular metabolic and signaling pathways by organizing
the pathway components in ordered microdomains on the cell surface. Cellular responses …

The'lipid raft'hypothesis has been a contentious topic over the past 5 years, with much of the
immunology community divided into'believers' and'nonbelievers'. The disagreement is due …