[HTML][HTML] Real-time PCR for Helicobacter pylori quantification and detection of clarithromycin resistance in gastric tissue from patients with gastrointestinal disorders

M Kargar, S Ghorbani-Dalini, A Doosti… - Research in microbiology, 2012 - Elsevier
Helicobacter pylori gram-negative bacteria commonly infect the human gastrointestinal (GI)
tract and are readily diagnosed by endoscopy. H. pylori infection causes a broad range of …

PCR-Based Diagnosis of Helicobacter pylori Infection and Real-Time Determination of Clarithromycin Resistance Directly from Human Gastric Biopsy Samples

SA Chisholm, RJ Owen, EL Teare… - Journal of Clinical …, 2001 - Am Soc Microbiol
ABSTRACT A novel PCR detection assay that amplifies the Helicobacter pylori-specific
vacuolating cytotoxin gene (vacA) and thus enables rapid diagnosis of infection is …

A novel stool PCR test for Helicobacter pylori may predict clarithromycin resistance and eradication of infection at a high rate

E Beckman, I Saracino, G Fiorini, C Clark… - Journal of clinical …, 2017 - Am Soc Microbiol
Clarithromycin-based regimens are commonly used as a first-line therapy for Helicobacter
pylori-positive patients; however, resistance to clarithromycin has led to treatment failures …

Fast and Accurate Quantitative Detection of Helicobacter pylori and Identification of Clarithromycin Resistance Mutations in H. pylori Isolates from Gastric Biopsy …

C Lascols, D Lamarque, JM Costa… - Journal of clinical …, 2003 - Am Soc Microbiol
Rapid identification of patients infected with clarithromycin-resistant Helicobacter pylori
without the need for culture can help to avoid useless prescriptions of clarithromycin. We …

[HTML][HTML] Real-time polymerase chain reaction for the detection of Helicobacter pylori and clarithromycin resistance

JH Noh, JY Ahn, J Choi, YS Park, HK Na, JH Lee… - Gut and …, 2023 - ncbi.nlm.nih.gov
Methods A total of 70 specimens with confirmed H. pylori infection in culture were enrolled
and analyzed in this prospective study. All specimens were subjected to RT-PCR assay …

Development of a Highly Sensitive Method for Detection of Clarithromycin-Resistant Helicobacter pylori from Human Feces

E Rimbara, N Noguchi, T Yamaguchi, K Narui… - Current …, 2005 - Springer
Gastric infection of clarithromycin (CAM)-resistant Helicobacter pylori is one of the major
causes of failure to eradicate this organism. A noninvasive and useful method for the …

Validation of a Fluorescence In Situ Hybridization Method Using Peptide Nucleic Acid Probes for Detection of Helicobacter pylori Clarithromycin Resistance in Gastric …

L Cerqueira, RM Fernandes, RM Ferreira… - Journal of Clinical …, 2013 - Am Soc Microbiol
Here, we evaluated a previously established peptide nucleic acid-fluorescence in situ
hybridization (PNA-FISH) method as a new diagnostic test for Helicobacter pylori …

Development and Validation of Multiplex Quantitative PCR Assay for Detection of Helicobacter pylori and Mutations Conferring Resistance to Clarithromycin and …

H Binmaeil, A Hanafiah, I Mohamed Rose… - Infection and Drug …, 2021 - Taylor & Francis
Aims and Objectives More than half of the world's population is infected with Helicobacter
pylori, which can cause chronic gastritis. WHO has regarded clarithromycin-resistant H …

Rapid screening of clarithromycin resistance in Helicobacter pylori by pyrosequencing

KA Moder, F Layer, W König… - Journal of medical …, 2007 - microbiologyresearch.org
Helicobacter pylori infections can be effectively treated with clarithromycin, a macrolide, in
combination with other antibiotics, such as amoxicillin, tetracycline or metronidazole. The …

[HTML][HTML] PCR detection of clarithromycin-susceptible and-resistant Helicobacter pylori from formalin-fixed, paraffin-embedded gastric biopsies

BH Schmitt, MA Regner, KA Mangold, RB Thomson Jr… - Modern pathology, 2013 - Elsevier
Antimicrobial resistance to clarithromycin is a growing concern in the treatment of
Helicobacter pylori and is associated with three major point mutations of the 23S rRNA …