Background—The effect of β-blockers on infarct size when used in conjunction with primary
percutaneous coronary intervention is unknown. We hypothesize that metoprolol reduces …

Objectives: The goal of this trial was to study the long-term effects of intravenous (IV)
metoprolol administration before reperfusion on left ventricular (LV) function and clinical …

Background: Pre-reperfusion administration of intravenous (IV) metoprolol reduces infarct
size in ST-segment elevation myocardial infarction (STEMI). Objectives: This study sought to …

Background: The impact of intravenous (IV) beta-blockers before primary percutaneous
coronary intervention (PPCI) on infarct size and clinical outcomes is not well established …

BACKGROUND: Myocardial infarct size is a strong predictor of cardiovascular events.
Intravenous metoprolol before coronary reperfusion has been shown to reduce infarct size; …

Early metoprolol administration protects against myocardial ischemia–reperfusion injury, but
its effect on infarct size progression (ischemic injury) is unknown. Eight groups of pigs (total …

Background Despite previous randomised trials of early β-blocker therapy in the emergency
treatment of myocardial infarction (MI), uncertainty has persisted about the value of adding it …

Background—β-Blockers improve clinical outcome when administered early after acute
myocardial infarction. However, whether β-blockers actually reduce the myocardial infarction …

The effects of metoprolol treatment in patients surviving acute myocardial infarction have
been investigated in a double-blind randomized study. The patients were stratified …

Objectives: We sought to examine the effect of intravenous beta-blockers administered
before primary percutaneous coronary intervention (PCI) on survival and myocardial …