Functional MRI (fMRI) in established Alzheimer's disease (AD) shows regionally altered
blood oxygenation level dependent (BOLD) responses. Mild cognitive impairment (MCI) is …

A growing body of evidence suggests that a preclinical phase of Alzheimer's disease (AD)
exists several years or more prior to the overt manifestation of clinical symptoms and is …

Background: Alzheimer's disease (AD) is a neurodegenerative disorder that may benefit
from early diagnosis and intervention. Therefore, there is a need to identify early biomarkers …

Purpose: To prospectively identify brain regions in which task-related changes in activation
during a memory encoding task, measured with functional magnetic resonance (MR) …

Functional magnetic resonance imaging (fMRI) studies of the medial temporal lobe have
primarily made use of the blood oxygenation level dependent (BOLD) response to neural …

Simultaneous resting state functional magnetic resonance imaging (rsfMRI)–resting state
electroencephalography (rsEEG) studies in healthy adults showed robust positive …

Brain activation in studies using blood oxygenation level dependent (BOLD) FMRI is
associated with an increase in T2* weighted signal between baseline and an active …

Visuospatial dysfunction including defects in motion perception in Alzheimer's disease (AD)
and mild cognitive impairment (MCI) are clues to search for potential in vivo biomarkers. In …

Several studies have demonstrated age-related regional differences in the magnitude of the
BOLD signal using task-based fMRI. It has been suggested that functional changes reflect …

Recent functional imaging studies have indicated that the pathophysiology of Alzheimer's
disease (AD) can be associated with the changes in spontaneous low-frequency (< 0.08 Hz) …