Genes disrupted in schizophrenia may be revealed by de novo mutations in affected
persons from otherwise healthy families. Furthermore, during normal brain development …

We performed integrated gene coexpression network analysis on two large microarray-
based brain gene expression data sets generated from the prefrontal cortex obtained post …

Objective Neurodevelopmental disorders presumably involve events that occur during brain
development. The authors hypothesized that neuropsychiatric disorders considered to be …

Large-scale genomic studies of schizophrenia have identified hundreds of genetic loci
conferring risk to the disorder. This progress offers an important route toward defining the …

Genome-wide association studies have identified 108 schizophrenia risk loci, but biological
mechanisms for individual loci are largely unknown. Using developmental, genetic and …

Neuropathological and brain imaging studies suggest that schizophrenia may result from
neurodevelopmental defects. Cytoarchitectural studies indicate cellular abnormalities …

Context Schizophrenia is a common, highly heritable, neurodevelopmental mental illness,
characterized by genetic heterogeneity. Objective To identify abnormalities in the …

Schizophrenia is a severe neuropsychiatric disorder with a longstanding history of
neurobiological investigation. Although the underlying causal mechanisms remain …

Schizophrenia is a severe psychiatric disorder with high heritability. Consortia efforts and
technological advancements have led to a substantial increase in knowledge of the genetic …

A large portion of common variant loci associated with genetic risk for schizophrenia reside
within noncoding sequence of unknown function. Here, we demonstrate promoter and …