OBJECTIVE: To estimate the effect of low-dose aspirin started in early pregnancy on the
incidence of preeclampsia and intrauterine growth restriction (IUGR). DATA SOURCES: A …

Background Preeclampsia and fetal growth restriction are major causes of perinatal death
and handicap in survivors. Randomized clinical trials have reported that the risk of …

Objective: To compare the effect of early administration of aspirin on the risk of preterm and
term preeclampsia. Method: A systematic review and meta-analysis of randomized …

Objective Data Preconception or early administration of low-dose aspirin might improve
endometrial growth, placental vascularization, and organogenesis. Most studies have …

Objective Data Metaanalyses of randomized controlled trials have reported contradictory
results about the effect of aspirin in the prevention of preeclampsia, both in terms of the …

Objective To evaluate the effect of aspirin dose on the incidence of all gestational age
preeclampsia and preterm preeclampsia. Data sources Electronic databases (Cochrane …

Objective To determine whether early administration of aspirin prevents severe and mild
preeclampsia. Study Design A systematic review and meta-analysis of randomized …

The aim of the present meta-analysis study was to evaluate the efficacy of low‑dose aspirin,
commenced at≤ 16 weeks of gestation, in preventing preterm and term preeclampsia, as …

Objective To study the effect of aspirin in the prevention of pre‐eclampsia in high‐risk
women. Design Randomised, double‐blinded, placebo‐controlled trial. Setting Maternity …

Context Low-dose aspirin is used for pre-eclampsia prophylaxis during pregnancy, but a
study that comprehensively investigates both maternal and perinatal outcomes from aspirin …