The RNA N6-methyladenosine modification landscape of human fetal tissues
S Xiao, S Cao, Q Huang, L Xia, M Deng, M Yang… - Nature cell …, 2019 - nature.com
A single genome gives rise to diverse tissues through complex epigenomic mechanisms,
including N 6-methyladenosine (m6A), a widespread RNA modification that is implicated in …
including N 6-methyladenosine (m6A), a widespread RNA modification that is implicated in …
N6-methyladenosine regulates maternal RNA maintenance in oocytes and timely RNA decay during mouse maternal-to-zygotic transition
Y Wu, X Xu, M Qi, C Chen, M Li, R Yan, X Kou… - Nature cell …, 2022 - nature.com
Abstract N 6-methyladenosine (m6A) and its regulatory components play critical roles in
various developmental processes in mammals. However, the landscape and function of …
various developmental processes in mammals. However, the landscape and function of …
m6A RNA modification controls cell fate transition in mammalian embryonic stem cells
Summary N6-methyl-adenosine (m 6 A) is the most abundant modification on messenger
RNAs and is linked to human diseases, but its functions in mammalian development are …
RNAs and is linked to human diseases, but its functions in mammalian development are …
Genetic drivers of m6A methylation in human brain, lung, heart and muscle
The most prevalent post-transcriptional mRNA modification, N 6-methyladenosine (m6A),
plays diverse RNA-regulatory roles, but its genetic control in human tissues remains …
plays diverse RNA-regulatory roles, but its genetic control in human tissues remains …
m6A-TSHub: Unveiling the Context-Specific m6A Methylation and m6A-Affecting Mutations in 23 Human Tissues
As the most pervasive epigenetic marker present on mRNAs and long non-coding RNAs
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
(lncRNAs), N 6-methyladenosine (m6A) RNA methylation has been shown to participate in …
[HTML][HTML] scDART-seq reveals distinct m6A signatures and mRNA methylation heterogeneity in single cells
Summary N 6-methyladenosine (m 6 A) is an abundant RNA modification that plays critical
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …
roles in RNA regulation and cellular function. Global m 6 A profiling has revealed important …
N6-methyladenosine–encoded epitranscriptomics
Abstract N 6-methyladenosine (m 6 A) is the most abundant internal modification in
eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m 6 A …
eukaryotic mRNA. Recent discoveries of the locations, functions and mechanisms of m 6 A …
m6A-LAIC-seq reveals the census and complexity of the m6A epitranscriptome
Abstract N 6-Methyladenosine (m6A) is a widespread, reversible chemical modification of
RNA molecules, implicated in many aspects of RNA metabolism. Little quantitative …
RNA molecules, implicated in many aspects of RNA metabolism. Little quantitative …
The biogenesis and precise control of RNA m6A methylation
N 6-Methyladenosine (m 6 A) is the most prevalent internal RNA modification in mRNA, and
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …
has been found to be highly conserved and hard-coded in mammals and other eukaryotic …
Topology of the human and mouse m6A RNA methylomes revealed by m6A-seq
D Dominissini, S Moshitch-Moshkovitz, S Schwartz… - Nature, 2012 - nature.com
An extensive repertoire of modifications is known to underlie the versatile coding, structural
and catalytic functions of RNA, but it remains largely uncharted territory. Although …
and catalytic functions of RNA, but it remains largely uncharted territory. Although …