Rationale: Mycobacterium tuberculosis is transmitted by infectious aerosols, but assessing
infectiousness currently relies on sputum microscopy that does not accurately predict the …

The concentration and size distribution of infectious aerosols produced by patients with
pulmonary tuberculosis (TB) has never been directly measured. We aimed to assess the …

Rationale: Airborne transmission of Mycobacterium tuberculosis results from incompletely
characterized host, bacterial, and environmental factors. Sputum smear microscopy is …

Background. Tuberculosis disease develops in only 5%–10% of humans infected with
Mycobacterium tuberculosis. The mechanisms underlying this variability remain poorly …

Cough has long been implicated in the production of infectious aerosol leading to
transmission of tuberculosis (TB). However, prevalence studies frequently identify …

Cough is a predominant feature of respiratory infection and, in tuberculosis, is of prime
importance for transmitting infection. Tuberculosis is transmitted by the air, yet the process …

Rationale: Interrupting tuberculosis (TB) transmission requires an improved understanding
of how and when the causative organism, Mycobacterium tuberculosis (Mtb), is aerosolized …

Background. Cough is the major determinant of tuberculosis transmission. Despite this,
there is a paucity of information regarding characteristics of cough frequency throughout the …

It is generally recognized that most nosocomial infections are spread by exposure to
expelled particles at close range (usually within 1 m) or through contact. Although the Korea …

Experimental animal models of tuberculosis (TB) have convincingly demonstrated that
inhaled dose predicts immunopathology and survival. In contrast, the importance of inhaled …