S100B is the principal calcium-binding protein of astrocytes and known to be secreted to
extracellular space. Although secreted S100B has been reported to promote neurite …

J. Neurochem.(2011) 117, 321–332. Abstract S100B is a soluble protein secreted by
astrocytes that exerts pro‐survival or pro‐apoptotic effects depending on the concentration …

To find out if the astrocytic protein S100B involves its autocrine effects via RAGE we
investigated the capacity of astrocytes to upregulate IL-6 and TNF-alpha expression by …

Abstract S100B, a Ca2+‐modulated protein with both intracellular and extracellular
regulatory roles, is most abundant in astrocytes, is expressed in various amounts in several …

Extracellular S100B dramatically increases after brain injury. While low S100B levels are
neuroprotective, micromolar S100B levels have shown in vitro to activate microglia and …

High levels of the inflammatory molecule S100B protein have been identified in sera from
several perinatal inflammatory conditions involving myelin damage and associated with an …

S100B is a calcium-binding protein expressed and secreted by astrocytes, playing a
neurotrophic role in neighboring cells. A protective role of the S100B against glutamate …

The Ca 2+-binding protein of the EF-hand type, S100B, is abundantly expressed in and
secreted by astrocytes, and release of S100B from damaged astrocytes occurs during the …

The Ca2+-modulated protein, S100B, is expressed in high abundance in and released by
astrocytes. At the low levels normally found in the brain, extracellular S100B acts as a …

Several molecules have been shown to be involved in glial-neuronal communication,
including S100B, an astrocyte-derived neurotrophic cytokine. Extracellular S100B protects …