Context: SARS CoV 2 induced cytokine storm is the major cause of COVID 19 related deaths. Patients have been treated with drugs that work by inhibiting a specific protein partly …
Severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) induced cytokine storm is the major cause of COVID-19 related deaths. Patients have been treated with drugs that …
P Ramesh, S Veerappapillai, R Karuppasamy - Gene reports, 2021 - Elsevier
The current outbreak of coronavirus disease (COVID-19) has been affecting millions of people and has caused devastating mortality worldwide. Moreover, it is to be noted that …
Motivation COVID-19 has several distinct clinical phases: a viral replication phase, an inflammatory phase and in some patients, a hyper-inflammatory phase. High mortality is …
M Chan, S Vijay, J McNevin, MJ McElrath… - Molecular systems …, 2021 - embopress.org
Abstract Although 15–20% of COVID‐19 patients experience hyper‐inflammation induced by massive cytokine production, cellular triggers of this process and strategies to target them …
COVID-19 is a global pandemic impacting the daily living of millions. As variants of the virus evolve, a complete comprehension of the disease and drug targets becomes a decisive …
In COVID-19, patients in severe condition often suffer from a major complication that leads to lung injury, ARDS and possibly death: the cytokine storm. The cytokine storm is composed of …
Cytokine storm (CS) is an acute hyperinflammatory response that may be responsible for critical illness in many conditions, including viral infections, cancer, sepsis (bacterial), and …
COVID-19 is a viral infection caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that killed a large number of patients around the world. A hyperinflammatory …