[PDF][PDF] Genes affecting in cytokine storm as therapeutic targets in COVID-19 infection.

M Behfar, F Forouzesh - Journal of Human Genetics & …, 2022 - humangeneticsgenomics.ir
Background: A cytokine storm is an abnormal host immune system response and a principal
responsibility for the incidence of acute respiratory distress syndrome. The existence of the …

Cytokine Storm and its Implication in Coronavirus disease 2019 (COVID-19)

C Datta, A Bhattacharjee - Journal of …, 2020 - immunologyresearchjournal.com
Abstract Corona virus disease 2019 (COVID-19), is a viral disease caused by novel corona
virus known as severe acute respiratory syndrome corona virus 2 (SARS-CoV-2). The …

Identification of toll‐like receptor 5 and acyl‐CoA synthetase long chain family member 1 as hub genes are correlated with the severe forms of COVID‐19 by Weighted …

L Wang, Z Mao, F Shao - IET Systems Biology, 2023 - Wiley Online Library
Since a 25% mortality rate occurred in critical Coronavirus disease 2019 (COVID‐19)
patients, investigating the potential drivers remains to be important. Here, the authors …

Comprehensive investigation of RNA‐sequencing dataset reveals the hub genes and molecular mechanisms of coronavirus disease 2019 acute respiratory distress …

W Deng, J Zeng, S Lu, C Li - IET systems biology, 2021 - Wiley Online Library
The goal of this study is to reveal the hub genes and molecular mechanisms of the
coronavirus disease 2019 (COVID‐19) acute respiratory distress syndrome (ARDS) based …

Targeting macrophages as a therapeutic option in coronavirus disease 2019

M Gracia-Hernandez, EM Sotomayor… - Frontiers in …, 2020 - frontiersin.org
Immune cells of the monocyte/macrophage lineage are characterized by their diversity,
plasticity, and variety of functions. Among them, macrophages play a central role in antiviral …

CCL2 Promotes Novel Coronavirus-Mediated Inflammatory Responses on Macrophages

F Ding, M Dai, X Kang, X Zhang, L Li… - Clinical and …, 2023 - utpjournals.press
Purpose The hyperinflammatory response is one of the main complications associated with
novel coronavirus disease 2019 (COVID-19), and there is no effective treatment for cytokine …

Role of inflammatory cytokines in COVID-19 patients: A review on molecular mechanisms, immune functions, immunopathology and immunomodulatory drugs to …

AA Rabaan, SH Al-Ahmed, J Muhammad, A Khan… - Vaccines, 2021 - mdpi.com
Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2), is a severe pandemic of the current century. The vicious …

Targeting inflammatory cytokine storm to fight against COVID-19 associated severe complications

R Hirawat, MA Saifi, C Godugu - Life sciences, 2021 - Elsevier
Such testing and trying time probably never seen before in the human history. The novel
coronavirus disease abbreviated as COVID-19 is the ongoing health crisis which entered …

Surviving the storm: cytokine biosignature in SARS-CoV-2 severity prediction

R Ahmad, M Haque - Vaccines, 2022 - mdpi.com
Simple Summary The world has been stricken mentally, physically, and economically by the
COVID-19 virus. However, while SARS-CoV-2 viral infection results in mild flu-like symptoms …

Bioinformatic approaches for identification of potential repurposable drugs in COVID-19

M Mandal, S Mandal - Journal of Drug Delivery and Therapeutics, 2021 - jddtonline.info
Introduction: Repurposing existing drugs approved for other conditions is crucial to
identifying specific therapeutics against SARS-CoV-2 (severe acute respiratory syndrome …